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1. WO2022107032 - METHOD FOR PREPARING BIODEGRADABLE MICROCAPSULES AND MICROCAPSULES OBTAINED IN THIS MANNER

Publication Number WO/2022/107032
Publication Date 27.05.2022
International Application No. PCT/IB2021/060689
International Filing Date 18.11.2021
IPC
B01J 13/18 2006.1
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
13Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
02Making microcapsules or microballoons
06by phase separation
14Polymerisation, crosslinking
18In situ polymerisation with all reactants being present in the same phase
A01N 25/28 2006.1
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
25Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
26in coated particulate form
28Microcapsules
A23P 10/35 2016.1
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
PSHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
10Shaping or working of foodstuffs characterised by the products
30Encapsulation of particles, e.g. foodstuff additives
35with oils, lipids, monoglycerides or diglycerides
A61K 8/11 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
02characterised by special physical form
11Encapsulated compositions
A61K 9/48 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
C09B 67/02 2006.1
CCHEMISTRY; METALLURGY
09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES; MORDANTS; LAKES
67Influencing the physical, e.g. the dyeing or printing, properties of dyestuffs without chemical reaction, e.g. by treating with solvents; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
02Dyestuff preparations characterised by special physical forms, e.g. tablets, films
CPC
A01N 25/28
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
25Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, ; e.g. seed treatment or sequential application;
26in coated particulate form
28Microcapsules ; or nanocapsules
A23P 10/30
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
PSHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
10Shaping or working of foodstuffs characterised by the products
30Encapsulation of particles, e.g. foodstuff additives
A23P 10/35
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
PSHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
10Shaping or working of foodstuffs characterised by the products
30Encapsulation of particles, e.g. foodstuff additives
35with oils, lipids, monoglycerides or diglycerides
A61K 2800/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
10General cosmetic use
A61K 2800/412
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
40Chemical, physico-chemical or functional or structural properties of particular ingredients
41Particular ingredients further characterized by their size
412Microsized, i.e. having sizes between 0.1 and 100 microns
A61K 8/11
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
02characterised by special physical form
11Encapsulated compositions
Applicants
  • GEM INNOV [FR]/[FR]
Inventors
  • GUILLANEUF, Yohann
  • LEFAY, Catherine
  • GIGMES, Didier
  • HO, The Hien
  • OUDOUA, Kaouthar
  • RIBEIRO, Thierry
  • ORTAIS, Yves
Agents
  • SCHMIDT, Martin
Priority Data
201182918.11.2020FR
Publication Language French (fr)
Filing Language French (FR)
Designated States
Title
(EN) METHOD FOR PREPARING BIODEGRADABLE MICROCAPSULES AND MICROCAPSULES OBTAINED IN THIS MANNER
(FR) PROCEDE DE PREPARATION DE MICROCAPSULES BIODEGRADABLES ET MICROCAPSULES AINSI OBTENUES
Abstract
(EN) Method for manufacturing microcapsules comprising a wall made of polymer material containing an active substance, comprising the following steps: - preparing an oil phase comprising a poly(beta-aminoester) prepolymer, and an active substance constituting the phase to be encapsulated; - preparing an aqueous phase comprising at least one surfactant; - preparing an O/W (oil in water) emulsion by adding the oil phase to the aqueous phase; and - initiating radical polymerisation within the emulsion. A polymerisation initiator must be present in the aqueous and/or oil phase.
(FR) Procédé de fabrication de microcapsules comportant une paroi en matériau polymère renfermant une substance active, comprenant les étapes suivantes : Préparation d'une phase huileuse comprenant un pré-polymère de poly(béta- aminoester), et une substance active constituant la phase à encapsuler. Préparation d'une phase aqueuse comprenant au moins un tensioactif. Préparation d'une émulsion de type O/W (huile dans l'eau) par ajout de ladite phase huileuse à ladite phase aqueuse. Déclenchement de la polymérisation radicalaire au sein de ladite émulsion. Un amorceur de polymérisation doit être présent dans la phase aqueuse et/ou huileuse.
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