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1. WO2021184128 - METHODS OF TREATING A CORONAVIRUS INFECTION USING COLCHICINE

Publication Number WO/2021/184128
Publication Date 23.09.2021
International Application No. PCT/CA2021/050368
International Filing Date 19.03.2021
IPC
A61K 31/165 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
165having aromatic rings, e.g. colchicine, atenolol, progabide
A61K 31/56 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
A61K 31/616 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
60Salicylic acid; Derivatives thereof
612having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
616by carboxylic acids, e.g. acetylsalicylic acid
A61K 31/706 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
7052having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706containing six-membered rings with nitrogen as a ring hetero atom
A61K 39/395 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61K 9/28 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, lozenges or tablets
28Dragees; Coated pills or tablets
CPC
A61K 31/165
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
165having aromatic rings, e.g. colchicine, atenolol, progabide
A61K 31/706
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
7052having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706containing six-membered rings with nitrogen as a ring hetero atom
A61K 39/395
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 31/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
C07J 75/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
75Processes for the preparation of steroids in general
Applicants
  • INSTITUT DE CARDIOLOGIE DE MONTREAL [CA]/[CA]
Inventors
  • TARDIF, Jean-Claude
Agents
  • VICKERS, Mark F.
  • BOOCOCK, Graeme R.
  • DAMIANI, Michael
  • WOOD, David
  • ALLARD, Louis
  • KEELER, Todd
  • EVENSON, Brandon
  • BEHMANN, Curtis B.
  • DE KLEINE, Geoffrey
  • MARSMAN, Kathleen E.
  • NAUMAN, David A.
  • PUNDSACK, Scott
  • COGHLAN, Jeffrey
  • GORDON, Jeff
  • RAOUL, Jennifer
  • SOJONKY, Andrew D.
  • WEBB, Timothy
  • MUELLER-NEUHAUS, Jason R.
  • DYBWAD, Scott
  • SKINNER, Mhairi
Priority Data
62/992,42720.03.2020US
63/027,15319.05.2020US
63/148,31411.02.2021US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METHODS OF TREATING A CORONAVIRUS INFECTION USING COLCHICINE
(FR) MÉTHODES DE TRAITEMENT D'UNE INFECTION PAR LE CORONAVIRUS FAISANT APPEL À LA COLCHICINE
Abstract
(EN) Disclosed are methods of treating a coronavirus infection (e.g., a SARS-CoV-2 infection) using colchicine, and methods of treating Kawasaki Disease or Kawasaki Disease Shock Syndrome, e.g., by administering colchicine to a subject in need thereof.
(FR) L'invention concerne des méthodes de traitement d'une infection par le coronavirus (par exemple, une infection par le SARS-CoV-2) faisant appel à la colchicine, et des méthodes de traitement de la maladie de Kawasaki ou du syndrome de choc de la maladie de Kawasaki, par exemple, par administration de colchicine à un patient qui en a besoin.
Latest bibliographic data on file with the International Bureau