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1. (WO2013070603) COMPOSITIONS AND METHODS FOR TREATMENT OF KIDNEY DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/070603    International Application No.:    PCT/US2012/063705
Publication Date: 16.05.2013 International Filing Date: 06.11.2012
IPC:
A61K 38/00 (2006.01)
Applicants: CEDARS-SINAI MEDICAL CENTER [US/US]; 8700 Beverly Boulevard Los Angeles, California 90048 (US)
Inventors: CHYU, Kuang-Yuh; (US).
SHAH, Prediman K.; (US).
DIMAYUGA, Paul; (US)
Agent: LEVY, Seth, D.; Nixon Peabody LLP Gas Company Tower 555 West Fifth Street, 46th Floor Los Angeles, California 90013 (US)
Priority Data:
61/558,908 11.11.2011 US
Title (EN) COMPOSITIONS AND METHODS FOR TREATMENT OF KIDNEY DISEASES
(FR) COMPOSITIONS ET MÉTHODES DE TRAITEMENT DE MALADIES RÉNALES
Abstract: front page image
(EN)The invention provides compositions comprising immunogenic fragments of ApoB-100 for eliciting an immune response in a subject or vaccinating a subject, so as to treat, prevent, 5 inhibit and/or reduce symptoms of kidney diseases in the subject. The compositions include immunogenic fragments of ApoB-100, CD8+ T cells activated with immunogenic fragments of ApoB-100 or a combination thereof.
(FR)L'invention concerne des compositions comprenant des fragments immunogènes d'ApoB-100 destinées à déclencher une réponse immunitaire chez un sujet ou à la vaccination d'un sujet, afin de traiter, prévenir, inhiber et/ou réduire des symptômes de maladies rénales chez le sujet. Des compositions comprennent des fragments immunogènes d'ApoB-100, des lymphocytes T CD8+ activés par des fragments immunogènes d'ApoB-100 ou une combinaison de ceux-ci.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)