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1. WO2021029684 - PEPTIDE-COMPLEXED MICRONEEDLE AND COSMETIC COMPOSITION COMPRISING SAME

Publication Number WO/2021/029684
Publication Date 18.02.2021
International Application No. PCT/KR2020/010717
International Filing Date 13.08.2020
IPC
A61K 8/98 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
96containing materials, or derivatives thereof, of undetermined constitution
98of animal origin
A61K 8/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
02characterised by special physical form
A61K 8/64 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
64Proteins; Peptides; Derivatives or degradation products thereof
A61K 8/25 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
19containing inorganic ingredients
25Silicon; Compounds thereof
A61Q 19/08 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19Preparations for care of the skin
08Anti-ageing preparations
CPC
A61K 8/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
02characterised by special physical form
A61K 8/25
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
19containing inorganic ingredients
25Silicon; Compounds thereof
A61K 8/64
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
64Proteins; Peptides; Derivatives or degradation products thereof
A61K 8/98
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
96containing materials, or derivatives thereof of undetermined constitution
98of animal origin
A61Q 19/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19Preparations for care of the skin
08Anti-ageing preparations
Applicants
  • 주식회사 에스알바이오텍 SR BIOTEK INC. [KR]/[KR]
Inventors
  • 송병호 SONG, Byung Ho
  • 정광택 JEONG, Kwang Taek
  • 홍순정 HONG, Soon Jeong
  • 지민재 JI, Min Jae
  • 남다영 NAM, Da Yeong
  • 김미선 KIM, Mi Sun
  • 엄기남 UHM, Ki Nam
  • 곽지나 KWAK, Ji Na
Agents
  • 특허법인(유한)해담 HAEDAM IP GROUP
Priority Data
10-2019-009937614.08.2019KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) PEPTIDE-COMPLEXED MICRONEEDLE AND COSMETIC COMPOSITION COMPRISING SAME
(FR) MICRO-AIGUILLE COMPLEXÉE PAR UN PEPTIDE ET COMPOSITION COSMÉTIQUE LA COMPRENANT
(KO) 펩타이드 복합 마이크로니들 및 이를 포함하는 화장품 조성물
Abstract
(EN)
Disclosed in the present invention is a peptide-complexed microneedle as represented by chemical formula 1. The peptide-complexed microneedle can ultimately increase a collagen forming effect via complexation of a specific combination of peptides, which are a functional material for cosmetics that has low penetration and absorption in the skin, wherein a cosmetic composition comprising the peptide-complexed microneedle, due to significantly improved collagen formation, is effective for the reduction of skin wrinkles, in particular, the reduction of deep wrinkles. [Chemical formula 1] MN-S-S-D In chemical formula 1: MN is a microneedle containing silica (SiO2); S-S is a disulfide bond; and D is a mixture with a hexapeptide-derived residue and a tripeptide-derived residue, or a mixture with a pentapeptide-derived residue, a hexapeptide-derived residue, and a tripeptide-derived residue, wherein the tripeptide-derived residue is 30 ppm or less in terms of the bonding amount.
(FR)
La présente invention concerne une micro-aiguille complexée par un peptide telle que représentée par la formule chimique 1. La micro-aiguille complexée par un peptide peut en finalité augmenter un effet de formation de collagène par complexation d'une combinaison spécifique de peptides, qui représentent une matière fonctionnelle pour des produits cosmétiques présentant une faible pénétration et une faible absorption dans la peau, une composition cosmétique comprenant la micro-aiguille complexée par un peptide, du fait de la formation significativement améliorée de collagène, étant efficace pour la réduction des rides de la peau, en particulier, la réduction des rides profondes. [Formule chimique 1] MN-S-S-D. Dans la formule chimique 1 : MN représente une micro-aiguille contenant de la silice (SiO2) ; S-S représente une liaison disulfure ; et D représente un mélange comprenant un résidu dérivé d'hexapeptide et un résidu dérivé de tripeptide ou un mélange comprenant un résidu dérivé de pentapeptide, un résidu dérivé d'hexapeptide et un résidu dérivé de tripeptide, le résidu dérivé de tripeptide représentant 30 ppm ou moins en termes de quantité de liaison.
(KO)
본 발명은 다음 화학식 1로 표시되는, 펩타이드 복합 마이크로니들을 개시하며, 이는 피부로의 침투 내지 흡수율이 낮은 화장품 기능성 원료인 펩타이드를 특정 조합으로 복합화하여 궁극적으로 콜라겐 생성효과를 현저히 향상시킬 수 있는 펩타이드 복합 마이크로니들을 얻을 수 있고, 이러한 펩타이드 복합 마이크로니들을 포함하는 화장품 조성물은 콜라겐 생성율이 현저히 향상됨으로써 주름개선, 특히 깊은 주름 개선에 효과적이다. [화학식 1] MN-S-S-D 상기 화학식 1에서, MN은 실리카(SiO 2) 함유 마이크로 니들이고, S-S는 디설파이드 결합이며, D는 트리펩타이드 유래의 잔기와 헥사펩타이드 유래의 잔기와의 혼합물 또는 트리펩타이드 유래의 잔기, 헥사펩타이드 유래의 잔기 및 펜타펩타이드 유래의 잔기와의 혼합물이며, 단, 트리펩타이드 유래의 잔기는 그 결합량이 30ppm 이내임.
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