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1. WO2021207155 - AIRWAY EPITHELIAL ALKALINE THERAPY TO TREAT VIRAL RESPIRATORY INFECTION

Publication Number WO/2021/207155
Publication Date 14.10.2021
International Application No. PCT/US2021/025915
International Filing Date 06.04.2021
IPC
A61K 35/42 2015.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
42Respiratory system, e.g. lungs, bronchi or lung cells
A61L 27/38 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for prostheses or for coating prostheses
36containing ingredients of undetermined constitution or reaction products thereof
38Animal cells
A61L 27/56 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for prostheses or for coating prostheses
50Materials characterised by their function or physical properties
56Porous or cellular materials
CPC
A61K 35/42
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
42Respiratory system, e.g. lungs, bronchi or lung cells
A61K 9/0078
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
007Pulmonary tract; Aromatherapy
0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy;
0078for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
Applicants
  • THE TRUSTEES OF INDIANA UNIVERSITY [US]/[US]
  • AIRBASE BREATHING COMPANY, LLC. [US]/[US]
Inventors
  • DAVIS, Michael D.
  • GILK, Stacey D.
  • GASTON, Benjamin
  • ROBINSON, Christopher M.
  • EZZEDDINE, Diala
Agents
  • PILCHER, Jessamine G.
  • ADDISON, Bradford G.
Priority Data
63/005,84606.04.2020US
63/019,06001.05.2020US
63/056,13624.07.2020US
63/117,62324.11.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) AIRWAY EPITHELIAL ALKALINE THERAPY TO TREAT VIRAL RESPIRATORY INFECTION
(FR) THÉRAPIE ALCALINE DE L'ÉPITHÉLIUM RESPIRATOIRE POUR TRAITER UNE INFECTION RESPIRATOIRE VIRALE
Abstract
(EN) The present disclosure relates to a method of treating or preventing a viral infection by raising the pH of the airways of a subject. The effect can be mediated directly by administering a pharmaceutically acceptable basic solution. Additionally, the method provides co-administering an anti-viral composition to the subject.
(FR) La présente invention concerne une méthode de traitement ou de prévention d'une infection virale par augmentation du pH des voies respiratoires d'un sujet. L'effet peut être induit directement par l'administration d'une solution basique pharmaceutiquement acceptable. De plus, le procédé consiste à co-administrer une composition antivirale au sujet.
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