WO2019101490 METHODS OF MODULATING ALK

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Publication Number WO/2019/101490

Publication Date 31.05.2019

International Application No. PCT/EP2018/079923

International Filing Date 01.11.2018

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Applicants

SOCIETE DES PRODUITS NESTLE S.A. [CH]/[CH]

Inventors

GHELDOF, Nele
VALSESIA, Armand
HAGER, Jorg

Agents

KAMIBAYASHI, Lynne

Priority Data

17202802.9

21.11.2017

Publication Language English (en)

Filing Language English (EN)

Designated States

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Title

(EN) METHODS OF MODULATING ALK

(FR) PROCÉDÉS DE MODULATION D'ALK

Abstract

(EN) An agent capable of decreasing the activity of ALK for use in supporting weight maintenance and/or treating or preventing obesity.

(FR) L'invention concerne un agent apte à diminuer l'activité d'ALK, destiné à être utilisé pour aider à la stabilisation pondérale et/ou pour traiter ou prévenir l'obésité.

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
56	Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
57	substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone
573	substituted in position 21, e.g. cortisone, dexamethasone, prednisone

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N	MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15	Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09	Recombinant DNA-technology
11	DNA or RNA fragments; Modified forms thereof
113	Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3	Drugs for disorders of the metabolism
04	Anorexiants; Antiobesity agents

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
56	Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
57	substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone
573	substituted in position 21, e.g. cortisone, dexamethasone, prednisone

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N	MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15	Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09	Recombinant DNA-technology
11	DNA or RNA fragments; Modified forms thereof
113	Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

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1. WO2019101490 - METHODS OF MODULATING ALK

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q	MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1	Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68	involving nucleic acids
6876	Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes