WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
maximize
Machine translation
2. (US20160143886) Compositions And Method For Treatment Of Ischemic Neuronal Reperfusion Injury

Application Number: 15009492 Application Date: 28.01.2016
Publication Number: 20160143886 Publication Date: 26.05.2016
Publication Kind : A1
IPC:
A61K 31/4178
CPC:
A61K 31/4178
A61K 31/13
A61K 31/355
A61K 31/40
A61K 31/5513
A61K 31/5517
A61K 31/59
A61K 31/765
A61K 38/05
A61K 45/06
A62B 17/00
C07D 405/12
Y10T 428/2982
Applicants: Harpal S. Mangat
Howard University
Pradeep K. Karla
Inventors: Harpal S. Mangat
Pradeep K. Karla
Priority Data:
Title: (EN) Compositions And Method For Treatment Of Ischemic Neuronal Reperfusion Injury
Abstract:
(EN)

A method and composition for the treatment of ischemic neuronal reperfusion injury are provided. The composition can include a compound which is a combination of dantrolene and a residue of FMOC-valine. This composition can be used to provide a faster and higher CNS penetration than heretofore experienced with dantrolene. In another form, dantrolene may be formulated as a pro-drug, a pro-pro-drug and the like.