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1. WO2021207388 - COMPOSITIONS AND METHODS FOR TREATING COMPLICATIONS OF VIRAL INFECTIONS AND OTHER RESPIRATORY DISORDERS

Publication Number WO/2021/207388
Publication Date 14.10.2021
International Application No. PCT/US2021/026224
International Filing Date 07.04.2021
IPC
A61K 38/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61P 11/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
Applicants
  • FIRSTSTRING RESEARCH, INC. [US]/[US]
Inventors
  • GHATNEKAR, Gautam
  • GREK, Christina
  • JAMES, Carissa
  • MCQUISTON, Travis
Agents
  • MCLEOD, Bonnie Weiss
  • TEAGUE, Meghann K.
Priority Data
63/006,49807.04.2020US
63/134,46206.01.2021US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMPOSITIONS AND METHODS FOR TREATING COMPLICATIONS OF VIRAL INFECTIONS AND OTHER RESPIRATORY DISORDERS
(FR) COMPOSITIONS ET MÉTHODES POUR TRAITER DES COMPLICATIONS D'INFECTIONS VIRALES ET D'AUTRES TROUBLES RESPIRATOIRES
Abstract
(EN)
In one aspect, the present disclosure relates to treating or preventing a respiratory disease or disorder, by administering one or more compositions comprising an isolated polypeptide derived from an alpha Connexin. Exemplary respiratory diseases or disorders include acute respiratory distress syndrome (ARDS), alcoholic lung injury, acute lung injury (ALI), pulmonary fibrosis, idiopathy pulmonary fibrosis (IPF), and/or chronic obstructive pulmonary disease (COPD). In some aspects, the respiratory disease or disorder is a complication of a respiratory viral disease.
(FR)
Selon un aspect, la présente invention concerne le traitement ou la prévention d'une maladie ou d'un trouble respiratoire, par administration d'une ou de plusieurs compositions comprenant un polypeptide isolé dérivé d'une alpha connexine. Des exemples de maladies ou de troubles respiratoires comprennent le syndrome de détresse respiratoire aiguë (ARDS), une lésion pulmonaire alcoolique, une lésion pulmonaire aiguë (ALI), une fibrose pulmonaire, une fibrose pulmonaire idiopathique (IPF) et/ou une maladie pulmonaire obstructive chronique (COPD). Selon certains aspects, la maladie ou le trouble respiratoire est une complication d'une maladie virale respiratoire.
Latest bibliographic data on file with the International Bureau