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1. WO2021205297 - ADMINISTRATION OF mTOR INHIBITORS INTO THE CENTRAL NERVOUS SYSTEM

Publication Number WO/2021/205297
Publication Date 14.10.2021
International Application No. PCT/IB2021/052740
International Filing Date 01.04.2021
IPC
A61K 9/107 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
107Emulsions
A61K 31/436 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
4353ortho- or peri-condensed with heterocyclic ring systems
436the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
A61K 47/24 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
24containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
A61P 25/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
A61P 35/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Applicants
  • DOLCETTA, Diego [IT]/[IT]
Inventors
  • DOLCETTA, Diego
  • GIOVAGNOLI, Stefano
  • MAGINI, Alessandro
Agents
  • DELBARBA, Andrea
  • BIGGI, Cristina
Priority Data
10202000000722806.04.2020IT
Publication Language English (EN)
Filing Language Italian (IT)
Designated States
Title
(EN) ADMINISTRATION OF mTOR INHIBITORS INTO THE CENTRAL NERVOUS SYSTEM
(FR) ADMINISTRATION D'INHIBITEURS DE MTOR DANS LE SYSTÈME NERVEUX CENTRAL
Abstract
(EN)
The present invention relates to lipid vesicles containing at least one mTOR inhibitor for use in the treatment or prevention of a disease of the central nervous system. The invention also relates to a pharmaceutical composition comprising said lipid vesicles, preferably in the form of a solution, emulsion or suspension.
(FR)
La présente invention concerne des vésicules lipidiques contenant au moins un inhibiteur de mTOR pour une utilisation dans le traitement ou la prévention d'une maladie du système nerveux central. L'invention concerne également une composition pharmaceutique comprenant lesdites vésicules lipidiques, de préférence sous la forme d'une solution, d'une émulsion ou d'une suspension.
Latest bibliographic data on file with the International Bureau