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1. WO2021078988 - RECOMBINANT L-ASPARAGINASE

Publication Number WO/2021/078988
Publication Date 29.04.2021
International Application No. PCT/EP2020/079972
International Filing Date 23.10.2020
IPC
A61K 38/50 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43Enzymes; Proenzymes; Derivatives thereof
46Hydrolases (3)
50acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
A61P 35/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
02specific for leukemia
CPC
A61K 38/50
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43Enzymes; Proenzymes; Derivatives thereof
46Hydrolases (3)
50acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
A61P 35/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
02specific for leukemia
Applicants
  • JAZZ PHARMACEUTICALS IRELAND LTD. [IE]/[IE]
Inventors
  • CHOI, Mi Rim
  • LIN, Tong
  • SILVERMAN, Jeffrey
Agents
  • MARSHALL, Cameron John
  • COCKERTON, Bruce Roger
  • GOODFELLOW, Hugh Robin
  • TUNSTALL, Christopher Stephen
  • KIRSCH, Susan Edith
  • SMALL, Gary James
  • WARNER, James Alexander
  • BRUNNER, John Michael Owen
  • CHAPMAN, Desmond Mark
  • WISE, Daniel Joseph
  • OATES, Edward Christopher
  • MCGUIRE, Gillian Margaret
  • MORRIS, Claire Louise
  • COX, Jennifer Jane
  • GEORGIOU, Matthew
  • HOLLAND, David Christopher
  • BETTRIDGE, Paul Sebastian
  • DRAGOSAVAC, Susannah Marie
  • PREISSNER, Tanja Stephanie
  • LEATHLEY, Anna Elisabeth
  • HUSBAND, Benjamin
  • DUFFIELD, Stephen
  • ADAMS, Harvey Vaughan John
  • HOGGETT, Christopher James
  • GRABENSTEIN, Jens
  • MICHELL, Stephen Robert
  • DARBY, Richard John
  • BARRY, Isobel Amy
  • MCKINLEY, Elizabeth Anne
  • BIRCH, Matthew John
  • THEISEN, Andreas Robert
  • KAUFMAN, Paul Anthony
  • HANCOCK, Susan Marie
  • GOODMAN, Daniel
  • FLOWER, Chloe Natasha
  • DEMETRIADES, Emma Jayne
  • NEWELL, Richard James
  • WEGNER-CRIBBS, Natalia
  • STRAWSON, Annabel Frances
  • TYRRELL, Fergus
Priority Data
62/926,20125.10.2019US
63/047,22201.07.2020US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) RECOMBINANT L-ASPARAGINASE
(FR) L-ASPARAGINASE RECOMBINANTE
Abstract
(EN)
The present invention provides compositions and methods for treating a disease treatable by asparagine depletion in a human subject comprising administering to a human subject a recombinant L-asparaginase.
(FR)
La présente invention concerne des compositions et des procédés pour traiter une maladie pouvant être traitée par déplétion d'asparagine chez un sujet humain, comprenant l'administration à un sujet humain d'une L-asparaginase recombinante.
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