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1. WO2021042070 - DETERGENT-FREE SIMULTANEOUS MULTIOMICS SAMPLE PREPARATION METHOD USING NOVEL NEW VESICLE DESIGN

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Publication Number WO/2021/042070
Publication Date 04.03.2021
International Application No. PCT/US2020/048840
International Filing Date 31.08.2020
IPC
B25J 19/02 2006.1
BPERFORMING OPERATIONS; TRANSPORTING
25HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; HANDLES FOR HAND IMPLEMENTS; WORKSHOP EQUIPMENT; MANIPULATORS
JMANIPULATORS; CHAMBERS PROVIDED WITH MANIPULATION DEVICES
19Accessories fitted to manipulators, e.g. for monitoring, for viewing; Safety devices combined with or specially adapted for use in connection with manipulators
02Sensing devices
B25J 9/16 2006.1
BPERFORMING OPERATIONS; TRANSPORTING
25HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; HANDLES FOR HAND IMPLEMENTS; WORKSHOP EQUIPMENT; MANIPULATORS
JMANIPULATORS; CHAMBERS PROVIDED WITH MANIPULATION DEVICES
9Programme-controlled manipulators
16Programme controls
G01N 35/00 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
35Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/-G01N33/148; Handling materials therefor
CPC
B01L 2200/025
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
02Adapting objects or devices to another
025Align devices or objects to ensure defined positions relative to each other
B01L 2200/026
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
02Adapting objects or devices to another
026Fluid interfacing between devices or objects, e.g. connectors, inlet details
B01L 2200/0684
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
06Fluid handling related problems
0684Venting, avoiding backpressure, avoid gas bubbles
B01L 2300/042
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
04Closures and closing means
041Connecting closures to device or container
042Caps; Plugs
B01L 2300/043
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
04Closures and closing means
041Connecting closures to device or container
043Hinged closures
B01L 2300/0681
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
06Auxiliary integrated devices, integrated components
0681Filter
Applicants
  • PROTIFI, LLC [US]/[US]
Inventors
  • ZOUGMAN, Alexandre
  • WILSON, Sandra
  • WILSON, John, Paul
Agents
  • WANG, Ping
Priority Data
62/894,20130.08.2019US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) DETERGENT-FREE SIMULTANEOUS MULTIOMICS SAMPLE PREPARATION METHOD USING NOVEL NEW VESICLE DESIGN
(FR) PROCÉDÉ DE PRÉPARATION D'ÉCHANTILLONS MULTIOMIQUES SIMULTANÉS SANS DÉTERGENT AU MOYEN D'UNE NOUVELLE CONCEPTION DE VÉSICULE INNOVANTE
front page image
Abstract
(EN) A two-piece assembly for sequential through-matrix processing of solutions and/or solids is provided, the assembly having an inner vial which maintains and holds the matrix and an outer vial which is configured to receive the inner vial at the upper or lower parked positions, to respectively allow or impede passage of the solution through the matrix of the upper vial. Captured molecules can be treated with enzymes and/or chemistries in situ in the matrix, and without the need for the use of strong chaotropic agents such as urea or detergents like SDS.
(FR) La présente invention concerne un ensemble en deux parties pour le traitement séquentiel par matrice de solutions et/ou de solides, l'ensemble présentant un flacon interne qui maintient et supporte la matrice et un flacon externe qui est configuré pour recevoir le flacon interne au niveau des positions stationnées supérieure ou inférieure pour permettre ou empêcher respectivement le passage de la solution à travers la matrice du flacon supérieur. Des molécules capturées peuvent être traitées avec des enzymes et/ou des produits chimiques in situ dans la matrice et sans nécessiter l'utilisation de chaotropes forts tels que de l'urée ou des détergents tels que le SDS.
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