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1. US20220098621 - CRISPR COMPOSITIONS AND METHODS FOR PROMOTING GENE EDITING OF RIBOSOMAL PROTEIN S19 (RPS19) GENE

Office
United States of America
Application Number 17428880
Application Date 04.02.2020
Publication Number 20220098621
Publication Date 31.03.2022
Publication Kind A1
IPC
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87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
90Stable introduction of foreign DNA into chromosome
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9Enzymes; Proenzymes; Compositions thereof
14Hydrolases (3)
16acting on ester bonds (3.1)
22Ribonucleases ; RNAses, DNAses
A61K 35/28
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61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
A61P 7/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
7Drugs for disorders of the blood or the extracellular fluid
06Antianaemics
Applicants EmendoBio Inc.
Inventors David Baram
Lior Izhar
Asael Herman
Rafi Emmanuel
Michal Golan Mashiach
Joseph Georgeson
Title
(EN) CRISPR COMPOSITIONS AND METHODS FOR PROMOTING GENE EDITING OF RIBOSOMAL PROTEIN S19 (RPS19) GENE
Abstract
(EN)

RNA molecules comprising a guide sequence portion having 17-25 contiguous nucleotides containing nucleotides in the sequence set forth in any one of SEQ ID NOs 1-20465 and compositions, methods, and uses thereof.


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