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1. WO2011062730 - APPARATUS FOR DETECTING VOLATILE ORGANIC COMPOUNDS AND RELATED METHODS

Publication Number WO/2011/062730
Publication Date 26.05.2011
International Application No. PCT/US2010/053922
International Filing Date 25.10.2010
IPC
G01N 27/407 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
26by investigating electrochemical variables; by using electrolysis or electrophoresis
403Cells and electrode assemblies
406Cells and probes with solid electrolytes
407for investigating or analysing gases
C12Q 1/25 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
25involving enzymes not classifiable in groups C12Q1/26-C12Q1/7097
G01N 33/497 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
483Physical analysis of biological material
497of gaseous biological material, e.g. breath
A61B 5/08 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
08Measuring devices for evaluating the respiratory organs
C12Q 1/34 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
34involving hydrolase
CPC
G01N 33/497
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
483Physical analysis of biological material
497of gaseous biological material, e.g. breath
Applicants
  • EMPIRE TECHNOLOGY DEVELOPMENT LLC [US]/[US] (AllExceptUS)
  • GLITTER TECHNOLOGY LLP [SG]/[SG] (AllExceptUS)
  • SJONG, Angele [US]/[US] (UsOnly)
Inventors
  • SJONG, Angele
Agents
  • DINGES, Jason R.
Priority Data
12/619,90917.11.2009US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) APPARATUS FOR DETECTING VOLATILE ORGANIC COMPOUNDS AND RELATED METHODS
(FR) APPAREIL DE DÉTECTION DE COMPOSÉS ORGANIQUES VOLATILS ET PROCÉDÉ ASSOCIÉS
Abstract
(EN)
Disclosed are apparatuses for detecting one or more volatile organic compounds (VOCs). The apparatuses include a primary electrode and a reference electrode. One or more particles are coupled to the primary electrode and the one or more particles are coupled to one or more enzymes that are capable of undergoing a redox reaction with at least one VOC. The apparatus is configured to measure current or voltage generated between the primary electrode and the reference electrode in response to the redox reaction. The apparatuses can detect a variety of VOCs, including VOCs associated with lung cancer. Also disclosed are biosensor systems including the apparatuses and methods of using the biosensor systems.
(FR)
L'invention porte sur des appareils de détection d'un ou plusieurs composés organiques volatils (VOC). L'appareil comprend une électrode primaire et une électrode de référence. Une ou plusieurs particules sont couplées à l'électrode primaire et la ou les particules sont couplées à un ou plusieurs enzymes qui sont capables de subir une réaction redox avec au moins un composé organique volatil. L'appareil est configuré pour mesurer le courant ou la tension générée entre l'électrode primaire et l'électrode de référence en réponse à la réaction redox. Les appareils peuvent détecter une diversité de composés organiques volatils, y compris les composés organiques volatils associés au cancer du poumon. L'invention porte également sur des systèmes de biocapteur comprenant les appareils et sur des procédés d'utilisation des systèmes de biocapteur.
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