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1. WO2021060897 - NOVEL POCT DIAGNOSTIC SYSTEM FOR TRAUMATIC BRAIN INJURIES AND INFECTIOUS DISEASES

Publication Number WO/2021/060897
Publication Date 01.04.2021
International Application No. PCT/KR2020/013024
International Filing Date 25.09.2020
IPC
G01N 33/543 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
G01N 33/68 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
G01N 35/00 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
35Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/-G01N33/148; Handling materials therefor
CPC
A61B 5/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
A61B 5/1455
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
1455using optical sensors, e.g. spectral photometrical oximeters
A61B 5/157
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
15Devices for taking samples of blood
157Devices; characterised by integrated means for measuring characteristics of blood
G01N 33/543
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
G01N 33/574
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
G01N 33/68
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
Applicants
  • 주식회사 이지다이아텍 EZDIATECH INC. [KR]/[KR]
Inventors
  • 정용균 JUNG, Yong Gyun
  • 김주호 KIM, Joo Ho
Agents
  • 곽현규 KWAK, Hyun Kyu
Priority Data
10-2019-011956527.09.2019KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) NOVEL POCT DIAGNOSTIC SYSTEM FOR TRAUMATIC BRAIN INJURIES AND INFECTIOUS DISEASES
(FR) NOUVEAU SYSTÈME DE DIAGNOSTIC POCT POUR LÉSIONS CÉRÉBRALES TRAUMATIQUES ET MALADIES INFECTIEUSES
(KO) 새로운 외상성 뇌손상 및 감염병 POCT 진단시스템
Abstract
(EN)
The present invention relates to a POCT diagnostic system which is for traumatic brain injuries and infectious diseases, can quickly identify traumatic brain injuries, and is highly sensitive, and can thus accurately determine traumatic brain injuries. The present invention provides magnetic particles comprising: a core including a magnetically reactive metal; a shell layer surrounding the core and having a uniform thickness; and a capture probe used on the shell layer to capture biomaterial, wherein the capture probe includes an antibody that uses a biomarker as an antigen for diagnosing traumatic brain injuries or infectious diseases.
(FR)
La présente invention concerne un système de diagnostic POCT destiné aux lésions cérébrales traumatiques ainsi qu'aux maladies infectieuses, qui peut rapidement identifier des lésions cérébrales traumatiques et est hautement sensible, ce qui lui permet de déterminer avec précision des lésions cérébrales traumatiques. La présente invention concerne des particules magnétiques comprenant : un noyau comprenant un métal magnétiquement réactif ; une couche d'enveloppe entourant le noyau avec une épaisseur uniforme ; et une sonde de capture utilisée sur la couche d'enveloppe afin de capturer un biomatériau, ladite sonde de capture comprenant un anticorps qui utilise un biomarqueur en tant qu'antigène afin de diagnostiquer des lésions cérébrales traumatiques ou des maladies infectieuses.
(KO)
본 발명은 외상성 뇌손상을 신속하게 판별할 수 있으며, 높은 감도를 가짐에 따라 정확하게 외상성 뇌손상을 판정할 수 있는 외상성 뇌손상 및 감염병 POCT 진단시스템에 관한 것이다. 본 발명은 자석 반응 금속을 포함하는 코어; 상기 코어를 둘러싸며 균일한 두께를 갖는 쉘 층; 및 생체물질을 포획하기 위해 상기 쉘 층 위에 도입된 포획 프로브를 포함하되, 상기 포획 프로브는 외상성 뇌손상 또는 감염병 진단을 위한 바이오마커를 항원으로 하는 항체를 포함하는 것인 자성입자를 제공한다.
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