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Part 1:  1  2  3  4  5  6          Part 2:  A  B  C  D  E 
International application No. Applicant's or agent's file reference
PCT/EP2019/087062 CV-1121/PCT
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
27 December 2019 28 December 2018
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.
6. Drawings
The figure of the drawings to be published with the abstract is Figure No.     1    
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
none of the figures is to be published with the abstract.


     B01L 3/02 (2006.01)i; B01L 3/00 (2006.01)i
According to International Patent Classification (IPC) or to both national classification and IPC


Minimum documentation searched (classification system followed by classification symbols):
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, WPI Data


Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
US 2005282206 A1 (MICHAEL CORBETT JOHN [AU] ET AL) 22 December 2005 (2005-12-22)
paragraphs [0033], [0042], [0063], [0064], [0066], [0074], [0078]
figure 1
US 2018200677 A1 (LEE LUKE P [US] ET AL) 19 July 2018 (2018-07-19)
paragraphs [0062], [0063], [0075], [0078], [0079], [0091], [0092], [0104], [0109]
figures 2A, 2D
table 1
US 2007039866 A1 (SCHROEDER BENJAMIN G [US] ET AL) 22 February 2007 (2007-02-22)
paragraphs [0036], [0098], [0182], [0244], [0245], [0299], [0302]
figure 12
WO 2018126082 A1 (MIROCULIS INC [US]) 05 July 2018 (2018-07-05)
paragraphs [0067], [0068], [0070], [0071], [0074], [0081]
figures 1A, 1C
Special categories of cited documents:
document defining the general state of the art which is not considered to be of particular relevance
document cited by the applicant in the international application
earlier application or patent but published on or after the international filing date
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
document referring to an oral disclosure, use, exhibition or other means
document published prior to the international filing date but later than the priority date claimed
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
document member of the same patent family


Patent document cited in search report Publication date
Patent family member(s) Publication date
US 2005282206 A1
22 December 2005
US 2005282206 A1
WO 03016558 A1
22 December 2005
27 February 2003
US 2018200677 A1
19 July 2018
US 2018200677 A1
WO 2016172675 A1
19 July 2018
27 October 2016
US 2007039866 A1
22 February 2007
EP 1928570 A2
EP 1928571 A2
EP 2660482 A1
US 2007039866 A1
US 2007062583 A1
US 2007068573 A1
US 2007141593 A1
US 2010209916 A1
US 2011171748 A1
US 2013183210 A1
US 2016097087 A1
US 2016194697 A1
US 2016194702 A1
US 2019085387 A1
WO 2007024778 A2
WO 2007024798 A2
WO 2007024800 A2
WO 2007024914 A2
11 June 2008
11 June 2008
06 November 2013
22 February 2007
22 March 2007
29 March 2007
21 June 2007
19 August 2010
14 July 2011
18 July 2013
07 April 2016
07 July 2016
07 July 2016
21 March 2019
01 March 2007
01 March 2007
01 March 2007
01 March 2007
WO 2018126082 A1
05 July 2018
CA 3049416 A1
CN 110383061 A
EP 3563151 A1
US 2020061621 A1
WO 2018126082 A1
05 July 2018
25 October 2019
06 November 2019
27 February 2020
05 July 2018
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
20 March 2020
Date of mailing of the international search report:
30 March 2020
Authorized officer:
Bischoff, Laura
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