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1. WO2021202893 - DETECTING ADAPTIVE IMMUNITY TO CORONAVIRUS

Publication Number WO/2021/202893
Publication Date 07.10.2021
International Application No. PCT/US2021/025409
International Filing Date 01.04.2021
IPC
A61K 39/215 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
215Coronaviridae, e.g. avian infectious bronchitis virus
A61K 39/395 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61K 39/42 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
42viral
A61P 11/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 31/14 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
C07K 14/165 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
08RNA viruses
165Coronaviridae, e.g. avian infectious bronchitis virus
CPC
A61K 39/395
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies
A61K 39/42
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies
42viral
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 31/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
C07K 14/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
C12N 2770/20022
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2770ssRNA Viruses positive-sense
00011ssRNA Viruses positive-sense
20011Coronaviridae
20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Applicants
  • NONIGENEX, INC. [US]/[US]
Inventors
  • LAPOINTE, Jerome P.
  • SENYEI, Andrew
Agents
  • PENNEBAKER, Sara
Priority Data
63/005,16803.04.2020US
63/009,99214.04.2020US
63/013,42221.04.2020US
63/042,39422.06.2020US
63/052,92216.07.2020US
63/119,85401.12.2020US
63/161,86916.03.2021US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) DETECTING ADAPTIVE IMMUNITY TO CORONAVIRUS
(FR) DÉTECTION D'UNE IMMUNITÉ ADAPTATIVE CONTRE LE CORONAVIRUS
Abstract
(EN) Provided are devices, systems, methods and kits for determining whether a subject is immune to an infection by a disease-causing pathogen by measuring neutralizing antibodies against the disease-causing pathogen in a biological sample from the subject. The devices, systems, methods, and kits described herein are useful for confirming whether a vaccine against the disease-causing pathogen has elicited enough neutralizing antibodies to prevent a later infection, or lessen severity of disease caused by, the disease-causing pathogen. Such devices, systems, methods, and kits are also useful for detecting an infection in the subject.
(FR) L'invention concerne des dispositifs, des systèmes, des procédés et des kits visant à déterminer si un sujet est immun ou non à une infection par un pathogène provoquant la maladie par la mesure d'anticorps neutralisants luttant contre le pathogène provoquant la maladie dans un échantillon biologique provenant du sujet. Les dispositifs, systèmes, procédés et kits décrits dans la présente invention sont utiles pour confirmer si un vaccin contre le pathogène provoquant la maladie a engendré suffisamment d'anticorps neutralisants pour empêcher une infection ultérieure ou pour réduire la gravité de la maladie provoquée par le pathogène provoquant la maladie. Lesdits dispositifs, systèmes, procédés et kits sont également utiles pour détecter une infection chez le sujet.
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