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1. WO2009009786 - MAGNETO-MOTIVE ULTRASOUND DETECTION OF MAGNETIC NANOPARTICLES

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[ EN ]

CLAIMS

What is claimed is:

1. An apparatus for imaging, comprising:
a magnet for applying a magnetic field to a cell; and
an ultrasound detection system for detecting the cell with metallic nanoparticles interacting with the magnetic field.

2. The apparatus of claim 1 , wherein the ultrasound detection system is selected from the group consisting of color power Doppler, power Doppler, M-mode and B-scan modes.

3. The apparatus of claim 1, wherein the ultrasound detection system is equipped with an aperture and a broadband linear array transducer.

4. The apparatus of claim 1 , wherein the metallic nanoparticles are affected with energy capable of heating the detected cell.

5. The apparatus of claim 1, wherein the cell with metallic nanoparticles comprises at least a macrophage, a cancer cell, or a component of iron-laden tissue.

6. The apparatus of claim 1 , wherein the magnet is comprised of an iron-ferrite core and a solenoid coil.

7. A method for imaging, comprising the steps of:
applying a magnetic field to a cell, wherein the cell comprises a metallic composition and the magnetic field interacts with the metallic composition; and
detecting the cell by an ultrasound detection system and detecting the change in the cell caused by the interaction of the magnetic field with the metallic composition.

8. The method of claim 7, wherein the applying of the magnetic field to a cell uses a magnetic field generator.

9. The magnetic field generator of claim 8, comprising a solenoid, a function generator, a current amplifier and a regulated DC power supply.

10. The method of claim 7, wherein the metallic composition is located in the cell membrane, in the cell cytoplasm, or on the cell surface.

11. The method of claim 7, wherein the detecting the cell uses an ultrasound detection system selected from the group consisting of color power Doppler, power Doppler, M-mode and B- scan modes.

12. The method of claim 7, wherein the cell with metallic nanoparticles comprises at least a macrophage, a cancer cell, or a component of iron-laden tissue.