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1. CA2353574 - ANALOGUES OF GLP-1

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CLAIMS
What is claimed is:
1. A compound or pharmaceutically acceptable salt thereof, wherein said compound is: (Aib8,35)hGLP-1(7-36)NH2; (Aib8,35, Arg26,34, Lys36(N-tetradecanoyl))hGLP-1(7-36)NH2; (Aib8,35, Arg26, Lys34(N-tetradecanoyl))hGLP-1(7-36)NH2; (Aib8,35,37, Arg26,34, Lys38(N-tetradecanoyl))hGLP-1(7-38)NH2; (Aib8,35, Arg26,34, Lys36(N-decanoyl))hGLP-1(7-36)NH2; (Aib8,35, Arg26,34, Lys36(N-tetradecanoyl), β-Ala37)hGLP-1(7-37)-OH; (Aib8,35, Arg26,34, Lys 36(N-tetradecanoyl))hGLP-1(7-36)-OH; (Aib35)hGLP-1(7-36)NH2; (Aib8,35, A6c32)hGLP-1(7-36)NH2; (Aib8,35, Glu23)hGLP-1(7-36)NH2; (Aib8,24,35)hGLP-1(7-36)NH2, (Aib8,25,35)hGLP-1(7-36)NH2; (Aib8,35, Glu23, A6c32)hGLP-1(7-36)NH2; (Aib8,35, Arg26,34)hGLP-1(7-36)NH2;
(Aib8,35, Arg26,34, Lys36(Nε-octanoyl))hGLP-1(7-36)NH2; (Aib8,35, Arg26,34, Lys36(Nε-decanoyl))hGLP-1(7-36)OH; (Aib8,35, Lys25, Arg26,34, Lys36(Nε-decanoyl))hGLP-1(7-36)OH; (Aib8,35, Arg26,34, Ava37, Ado38)hGLP-1(7-38)NH2; (Aib8,35,Arg26,34, Asp37, Ava38, Ado39)hGLP-1(7-39)NH2; (Aib8,35,Arg26,34, Aun37)hGLP-1(7-37)NH2;
(Gly8, Aib35)hGLP-1(7-36)NH2; (Aib8,35, Phe31)hGLP-1(7-36)NH2; (Aib8,35, Nal31)hGLP-1(7-36)NH2; (Aib8,35, Nal28,31)hGLP-1(7-36)NH2; (Aib8,35, Arg26,34, Nal31)hGLP-1(7-36)NH2; (Aib8,35, Arg26,34, Phe31)hGLP-1(7-36)NH2; (Aib8,35, Nal19,31)hGLP-1(7-36)NH2; (Aib8,35, Nal12,31)hGLP-1(7-36)NH2;
(Aib8,35, Lys36(Nε-decanoyl))hGLP-1(7-36) NH2;
(Aib8,35, Arg34, Lys26(Nε-decanoyl))hGLP-1(7-36)NH2; or (Aib8,35, Arg26,34, Lys36(Nε-dodecanoyl))hGLP-1(7-36)NH2.
2. The compound (Aib8,35)hGLP-1(7-36)NH2, or a pharmaceutically acceptable salt thereof.
3. The compound (Aib8,35, Arg26,34, Phe31)hGLP-1(7-36)NH2, or a pharmaceutically acceptable salt thereof.
4. A composition comprising the compound or salt thereof according to claim 1, 2 or 3 and a pharmaceutically acceptable carrier or diluent.