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1. WO2020136292 - COMPOUNDS OF PHARMACEUTICAL INTEREST

Publication Number WO/2020/136292
Publication Date 02.07.2020
International Application No. PCT/ES2019/070865
International Filing Date 19.12.2019
IPC
C07J 9/00 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
9Normal steroids containing carbon, hydrogen, halogen, or oxygen, substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
A61K 31/575 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
575substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
A61P 35/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
CPC
A61K 31/575
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids
575substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07J 9/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
9Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Applicants
  • UNIVERSIDADE DE SANTIAGO DE COMPOSTELA [ES]/[ES]
  • UNIVERSITY OF WROCLAW [PL]/[PL]
Inventors
  • MARCINKOWSKA, Ewa
  • BERKOWSKA, Klaudia
  • MOURIÑO MOSQUERA, Antonio
  • SIGÜEIRO PONTE, Rita
  • GAIKWAD, Sunil
Agents
  • TORRENTE VILASANCHEZ, Susana
Priority Data
P20183129828.12.2018ES
Publication Language Spanish (ES)
Filing Language Spanish (ES)
Designated States
Title
(EN) COMPOUNDS OF PHARMACEUTICAL INTEREST
(ES) COMPUESTOS DE INTERÉS FARMACÉUTICO
(FR) COMPOSÉS D'INTÉRÊT PHARMACEUTIQUE
Abstract
(EN)
The present invention relates to compounds that can be defined as compounds derived from lithocholic acid and the metabolites thereof. For this reason, the compounds of the invention are named using the steroid numbering system. More particularly, the invention relates to compounds derived from lithocholic acid, to methods for obtaining same, to intermediate compounds from the synthesis thereof, and to their applications.
(ES)
Compuestos de interés farmacéutico. Los compuestos de la presente invención pueden definirse como derivados de ácido litocólicoy de sus metabolitos. Por este motivo los compuestos de la invención se nombran empleando el sistema de numeración de esteroides. Más en particular, se dirige a compuestos derivados del ácido litocólico, a los procedimientos de obtención de los mismos, a compuestos intermedios de su síntesis, y a sus aplicaciones.
(FR)
L'invention concerne des composés d'intérêt pharmaceutique. Les composés de la présente invention peuvent être définis comme dérivés d'acide lithocolique et leurs métabolites. A cet effet, les composés de l'invention sont désignés à l'aide du système de numérotation des stéroïdes. Plus particulièrement, l'invention concerne des composés dérivés de l'acide lithocolique, des procédés d'obtention de ceux-ci, des composés intermédiaires pour leur synthèse et leurs applications.
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