(12) International Application Status Report

Received at International Bureau: 30 January 2018 (30.01.2018)

Information valid as of: 12 March 2019 (12.03.2019)

Report generated on: 20 September 2019 (20.09.2019)

(10) Publication number: (43) Publication date: (26) Publication language:
WO 2019/06196204 April 2019 (04.04.2019) Chinese (ZH)

(21) Application number: (22) Filing date: (25) Filing language:
PCT/CN2018/07345719 January 2018 (19.01.2018) Chinese (ZH)

(31) Priority number(s): (32) Priority date(s): (33) Priority status:
201710916535.7 (CN)30 September 2017 (30.09.2017) Priority document received (in compliance with PCT Rule 17.1)

(51) International Patent Classification:
C07K 16/24 (2006.01); G01N 33/53 (2006.01); C07K 19/00 (2006.01); A61K 39/395 (2006.01)

(71) Applicant(s):
HUABO BIOPHARM (SHANGHAI) CO., LTD. [CN/CN]; 1st Floor, 1 Building, No. 538 Cailun Road China (Shanghai) Pilot Free Trade Zone Pudong New Area Shanghai 201203 (CN) (for all designated states)

(72) Inventor(s):
ZHU, Xiangyang; 1st Floor, 1 Building, No. 538 Cailun Road China (Shanghai) Pilot Free Trade Zone Pudong New Area Shanghai 201203 (CN)
YU, Haijia; 1st Floor, 1 Building, No. 538 Cailun Road China (Shanghai) Pilot Free Trade Zone Pudong New Area Shanghai 201203 (CN)
JIA, Huifeng; 1st Floor, 1 Building, No. 538 Cailun Road China (Shanghai) Pilot Free Trade Zone Pudong New Area Shanghai 201203 (CN)
YU, Ling; 1st Floor, 1 Building, No. 538 Cailun Road China (Shanghai) Pilot Free Trade Zone Pudong New Area Shanghai 201203 (CN)

(74) Agent(s):
XU & PARTNERS, LLC.; Room No. 106, Building No. 1 Universal High-Tech Plaza 958 Zhen Bei Road, Putuo District Shanghai 200333 (CN)

(54) Title (EN): ANTI-INTERLEUKIN-17A ANTIBODY, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
(54) Title (FR): ANTICORPS ANTI-INTERLEUKINE 17A, SON PROCÉDÉ DE PRÉPARATION ET SON APPLICATION
(54) Title (ZH): 一种抗白介素17A的抗体、其制备方法和应用

(57) Abstract:
(EN): Provided is an anti-interleukin-17A (IL-17A) antibody, a preparation method therefor and an application thereof. Specifically, said antibody is an anti-IL-17A monoclonal antibody. Said antibody can be combined in a highly specific way with an IL-17A antigen, has high affinity and low immunogenicity, and is used for preparing drugs for preventing or treating diseases related to IL-17A, such as any kind of inflammations or autoimmune diseases.
(FR): L'invention concerne un anticorps anti-interleukine 17A, son procédé de préparation et son application. L'invention concerne plus particulièrement un anticorps monoclonal anti-IL 17A. Ledit anticorps peut être combiné de manière hautement spécifique à un antigène IL-17A, présente une forte affinité et une faible immunogénicité, et sert à préparer des médicaments pour la prévention ou le traitement de maladies associées à l'IL-17A, telles que les inflammations quelles qu'elles soient ou les maladies auto-immunes.
(ZH): 提供了一种抗白介素17A(IL-17A)的抗体、其制备方法和应用。具体地,所述抗体为抗IL-17A单克隆抗体。所述抗体能够高特异性地结合IL-17A抗原,其具有很高的亲和力及很低的免疫原性,并且用于制备预防或治疗IL-17A相关的疾病如各种炎症或自身免疫疾病的药物。

International search report:
Received at International Bureau: 25 June 2018 (25.06.2018) [CN]

International Report on Patentability (IPRP) Chapter II of the PCT:
Not available

(81) Designated States:
AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
European Patent Office (EPO) : AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
African Intellectual Property Organization (OAPI) : BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG
African Regional Intellectual Property Organization (ARIPO) : BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW
Eurasian Patent Organization (EAPO) : AM, AZ, BY, KG, KZ, RU, TJ, TM