(12) International Application Status Report

Received at International Bureau: 14 January 2010 (14.01.2010)

Information valid as of: 03 March 2010 (03.03.2010)

Report generated on: 06 December 2019 (06.12.2019)

(10) Publication number: (43) Publication date: (26) Publication language:
WO 2010/07688408 July 2010 (08.07.2010) Japanese (JA)

(21) Application number: (22) Filing date: (25) Filing language:
PCT/JP2009/07181128 December 2009 (28.12.2009) Japanese (JA)

(31) Priority number(s): (32) Priority date(s): (33) Priority status:
61/193,826 (US)29 December 2008 (29.12.2008) Priority document received (in compliance with PCT Rule 17.1)

(51) International Patent Classification:
C07D 417/14 (2006.01); A61K 31/427 (2006.01); A61K 31/4439 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01); A61P 3/04 (2006.01); A61P 3/10 (2006.01); A61P 43/00 (2006.01)

(71) Applicant(s):
TAKEDA PHARMACEUTICAL COMPANY LIMITED [JP/JP]; 1-1, Doshomachi 4-chome, Chuo-ku, Osaka-shi, Osaka 5410045 (JP) (for all designated states except US)
YASUMA, Tsuneo [JP/JP]; c/o TAKEDA PHARMACEUTICAL COMPANY LIMITED, 17-85, Jusohonmachi 2-chome, Yodogawa-ku, Osaka-shi, Osaka 5328686 (JP) (for US only)
TAKAKURA, Nobuyuki [JP/JP]; c/o TAKEDA PHARMACEUTICAL COMPANY LIMITED, 17-85, Jusohonmachi 2-chome, Yodogawa-ku, Osaka-shi, Osaka 5328686 (JP) (for US only)
MIYAMOTO, Yasufumi [JP/JP]; c/o TAKEDA PHARMACEUTICAL COMPANY LIMITED, 17-85, Jusohonmachi 2-chome, Yodogawa-ku, Osaka-shi, Osaka 5328686 (JP) (for US only)

(72) Inventor(s):
YASUMA, Tsuneo; c/o TAKEDA PHARMACEUTICAL COMPANY LIMITED, 17-85, Jusohonmachi 2-chome, Yodogawa-ku, Osaka-shi, Osaka 5328686 (JP)
TAKAKURA, Nobuyuki; c/o TAKEDA PHARMACEUTICAL COMPANY LIMITED, 17-85, Jusohonmachi 2-chome, Yodogawa-ku, Osaka-shi, Osaka 5328686 (JP)
MIYAMOTO, Yasufumi; c/o TAKEDA PHARMACEUTICAL COMPANY LIMITED, 17-85, Jusohonmachi 2-chome, Yodogawa-ku, Osaka-shi, Osaka 5328686 (JP)

(74) Agent(s):
TAKASHIMA, Hajime; Meiji Yasuda Seimei Osaka Midosuji Bldg., 1-1, Fushimimachi 4-chome, Chuo-ku, Osaka-shi, Osaka 5410044 (JP)

(54) Title (EN): NOVEL FUSED RING COMPOUND AND USE THEREOF
(54) Title (FR): NOUVEAU COMPOSÉ CYCLIQUE CONDENSÉ ET UTILISATION DE CELUI-CI
(54) Title (JA): 新規縮合環化合物およびその用途

(57) Abstract:
(EN): Disclosed is a glucokinase activator or an agent for prevention/treatment of diabetes, obesity and the like, which contains a compound represented by formula (I), a salt thereof, or a prodrug thereof. (In the formula, the symbols are as defined in the description.)
(FR): La présente invention concerne un activateur de glucokinase ou un agent pour la prévention/le traitement du diabète, de l'obésité et similaire, qui contient un composé représenté par la formule (I), un sel de celui-ci, ou un promédicament de celui-ci. (Dans la formule, les symboles sont tels que définis dans la description).
(JA):  本発明は、式(I):[式中の各記号は、明細書記載と同意義である。] で表される化合物もしくはその塩またはそのプロドラッグを含有してなる糖尿病、肥満等の予防・治療剤、グルコキナーゼ活性化剤を提供する。

International search report:
Received at International Bureau: 28 January 2010 (28.01.2010) [JP]

International Report on Patentability (IPRP) Chapter II of the PCT:
Not available

(81) Designated States:
AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
European Patent Office (EPO) : AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR
African Intellectual Property Organization (OAPI) : BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG
African Regional Intellectual Property Organization (ARIPO) : BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW
Eurasian Patent Organization (EAPO) : AM, AZ, BY, KG, KZ, MD, RU, TJ, TM