(12) International Application Status Report

Received at International Bureau: 14 January 2010 (14.01.2010)

Information valid as of: 07 January 2011 (07.01.2011)

Report generated on: 10 December 2019 (10.12.2019)

(10) Publication number: (43) Publication date: (26) Publication language:
WO 2010/07358001 July 2010 (01.07.2010) Japanese (JA)

(21) Application number: (22) Filing date: (25) Filing language:
PCT/JP2009/00705121 December 2009 (21.12.2009) Japanese (JA)

(31) Priority number(s): (32) Priority date(s): (33) Priority status:
2008-326174 (JP)22 December 2008 (22.12.2008) Priority document received (in compliance with PCT Rule 17.1)

(51) International Patent Classification:
A61M 1/36 (2006.01); A61M 1/02 (2006.01)

(71) Applicant(s):
FUJITA HEALTH UNIVERSITY [JP/JP]; 1-98, Dengakugakubo, Kutsukake-cho, Toyoake-shi, Aichi 4701192 (JP) (for all designated states except US)
KANEKA CORPORATION [JP/JP]; 2-4, Nakanoshima 3-chome, Kita-ku, Osaka-shi, Osaka 5308288 (JP) (for all designated states except US)
KITAGUCHI, Nobuya [JP/JP]; Room 501, Bellvillage-kamishiota, 19, Aza Kamishiota, Narumi-cho, Midori-ku, Nagoya-shi, Aichi 4580835 (JP) (for US only)
KAWAGUCHI, Kazunori [JP/JP]; 109, Hirabari 3-chome, Tenpaku-ku, Nagoya-shi, Aichi 4680011 (JP) (for US only)

(72) Inventor(s):
KITAGUCHI, Nobuya; Room 501, Bellvillage-kamishiota, 19, Aza Kamishiota, Narumi-cho, Midori-ku, Nagoya-shi, Aichi 4580835 (JP)
KAWAGUCHI, Kazunori; 109, Hirabari 3-chome, Tenpaku-ku, Nagoya-shi, Aichi 4680011 (JP)

(74) Agent(s):
HAGINO, Mikiharu; 1-1, Technoplaza, Kakamigahara-shi, Gifu 5090109 (JP)

(54) Title (EN): Aβ-REMOVER, Aβ-REMOVING APPARATUS, AND Aβ REMOVAL METHOD
(54) Title (FR): EXTRACTEUR D'AMYLOÏDE Β, APPAREIL D'EXTRACTION D'AMYLOÏDE Β ET PROCÉDÉ D'EXTRACTION D'AMYLOÏDE Β
(54) Title (JA): Aβ除去材、Aβ除去器及びAβ除去システム

(57) Abstract:
(EN): Disclosed are a material capable of removing Aβ from a body fluid efficiently and use of the material, which are developed for the purpose of establishing a therapeutic or prophylactic method for Alzheimer's disease. Specifically disclosed is an amyloid-β protein remover which comprises a carrier made of a material selected from the group consisting of cellulose, silica, polyvinyl alcohol and activated carbon and having no alkyl chain or having a C1-18 alkyl chain on the surface thereof.
(FR): L'invention porte sur un produit capable d'extraire de manière efficace l'amyloïde β (Aβ) d'un fluide corporel et sur l'utilisation du matériau, développés dans le but d'établir un procédé thérapeutique ou prophylactique pour la maladie d'Alzheimer. L'invention porte spécifiquement sur un extracteur de protéine amyloïde β comprenant un support constitué d'un produit choisi dans le groupe constitué par la cellulose, la silice, l'alcool polyvinylique et le charbon actif et ne comportant pas de chaîne alkyle ou comportant une chaîne alkyle en C1-18 à sa surface.
(JA):  アルツハイマー病の治療又は予防法の確立を目指し、体液からAβを効率的に除去できる材料及びその用途を提供することを課題とする。セルロース、シリカ、ポリビニルアルコール及び活性炭からなる群より選択されるいずれかの材質の担体であって、その表面にアルキル鎖を有しないか、又はその表面に炭素数1~18のアルキル鎖を有する担体からなる、アミロイドβタンパク質除去材が提供される。

International search report:
Received at International Bureau: 04 February 2010 (04.02.2010) [JP]

International Report on Patentability (IPRP) Chapter II of the PCT:
Not available

(81) Designated States:
AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
European Patent Office (EPO) : AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR
African Intellectual Property Organization (OAPI) : BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG
African Regional Intellectual Property Organization (ARIPO) : BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW
Eurasian Patent Organization (EAPO) : AM, AZ, BY, KG, KZ, MD, RU, TJ, TM