(12) International Application Status Report

Received at International Bureau: 20 April 2005 (20.04.2005)

Information valid as of: Not available

Report generated on: 23 September 2019 (23.09.2019)

(10) Publication number: (43) Publication date: (26) Publication language:
WO 2005/10030227 October 2005 (27.10.2005) English (EN)

(21) Application number: (22) Filing date: (25) Filing language:
PCT/IB2005/00097113 April 2005 (13.04.2005) English (EN)

(31) Priority number(s): (32) Priority date(s): (33) Priority status:
60/563,265 (US)16 April 2004 (16.04.2004) Priority document received (in compliance with PCT Rule 17.1)
60/608,176 (US)07 September 2004 (07.09.2004) Priority document received (in compliance with PCT Rule 17.1)

(51) International Patent Classification:
C07C 227/42 (2006.01); C07C 229/48 (2006.01)

(71) Applicant(s):
GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. [HR/HR]; Prilaz baruna Filipovica 29 10000 Zagreb (HR) (for all designated states except US)
BAYER HEALTHCARE AG [DE/DE]; 51368 Leverkusen (DE) (for all designated states except US)
ZEGARAC, Miroslav [HR/HR]; Kresimirova 28 40323 Prelog (HR) (for US only)
MESTROVIC, Ernest [HR/HR]; Ivana Grande 41 43000 Bjelovar (HR) (for US only)
HULITA, Nada, Kosutic [HR/HR]; Brazilska 14 10090 Susedgrad (HR) (for US only)
FILIC, Darko [HR/HR]; Marice Baric 17 10000 Zagreb (HR) (for US only)
DUMIC, Miljenko [HR/HR]; Ivane Brlic Mazuranic 4 10000 Zagreb (HR) (for US only)
GRUNENBERG, Alfons [DE/DE]; Gneisenaustr. 15 41539 Dormagen (DE) (for US only)
KEIL, Brigit [DE/DE]; Sudetenstr. 36 40231 Dusseldorf (DE) (for US only)
CERIC, Helena [HR/HR]; Bribirska 5 10000 Zagreb (HR) (for US only)

(72) Inventor(s):
ZEGARAC, Miroslav; Kresimirova 28 40323 Prelog (HR)
MESTROVIC, Ernest; Ivana Grande 41 43000 Bjelovar (HR)
HULITA, Nada, Kosutic; Brazilska 14 10090 Susedgrad (HR)
FILIC, Darko; Marice Baric 17 10000 Zagreb (HR)
DUMIC, Miljenko; Ivane Brlic Mazuranic 4 10000 Zagreb (HR)
GRUNENBERG, Alfons; Gneisenaustr. 15 41539 Dormagen (DE)
KEIL, Brigit; Sudetenstr. 36 40231 Dusseldorf (DE)
CERIC, Helena; Bribirska 5 10000 Zagreb (HR)


(54) Title (EN): SOLID STATE FORMS OF (-)-(1R,2S)-2-AMINO-4-METHYLENE-CYCLOPENTANECARBOXYLIC ACID
(54) Title (FR): FORMES A L'ETAT SOLIDE D'ACIDE (-)-(1R,1S)-2-AMINO-4-METHYLENE-CYCLOPENTANECARBOXYLIQUE

(57) Abstract:
(EN): The present invention relates to the solid state forms α, β, δ, ε, and ζ of (-)-(1R,1S)-2-amino-4-methylene-cyclopentanecarboxylic acid, to the processes for their preparation, to pharmaceutical compositions containing the said solid state forms of (-)-(1R,1S)-2-amino-methylene-cyclopentanecarboxylic acid as the active ingredients as well as to a method of treatment using the same.
(FR): L'invention concerne des formes à l'état solide ?, ?, ?, e, et ? d'acide (-)-(1R,1S)-2-amino-4-méthylène-cyclopentanecarboxylique, leurs procédés de préparation, des compositions pharmaceutiques contenant les formes à l'état solide d'acide (-)-(1R,1S)-2-amino-méthylène-cyclopentanecarboxylique en tant que principes actifs ainsi qu'une méthode de traitement utilisant lesdites formes à l'état solide.

International search report:
Received at International Bureau: 06 October 2005 (06.10.2005) [EP]

International Report on Patentability (IPRP) Chapter II of the PCT:
Not available

(81) Designated States:
AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
European Patent Office (EPO) : AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR
African Intellectual Property Organization (OAPI) : BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG
African Regional Intellectual Property Organization (ARIPO) : BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW
Eurasian Patent Organization (EAPO) : AM, AZ, BY, KG, KZ, MD, RU, TJ, TM