(12) International Application Status Report

Received at International Bureau: 27 January 2005 (27.01.2005)

Information valid as of: Not available

Report generated on: 06 December 2019 (06.12.2019)

(10) Publication number: (43) Publication date: (26) Publication language:
WO 2005/06151107 July 2005 (07.07.2005) English (EN)

(21) Application number: (22) Filing date: (25) Filing language:
PCT/SE2004/00194220 December 2004 (20.12.2004) English (EN)

(31) Priority number(s): (32) Priority date(s): (33) Priority status:
60/531,644 (US)22 December 2003 (22.12.2003) Priority document received (in compliance with PCT Rule 17.1)

(51) International Patent Classification:
C07D 487/08 (2006.01)

(71) Applicant(s):
ASTRAZENECA AB [SE/SE]; S-151 85 Södertälje (SE) (for all designated states except US)
ERNST, Glen [US/US]; AstraZeneca Wilmington P.O. Box 15437 Wilmington, Delaware 19850-5437 (US) (for US only)
FRIETZE, William [US/US]; AstraZeneca Wilmington P.O Box 15437 Wilmington, Delaware 19850-5437 (US) (for US only)
JACOBS, Robert [US/US]; Scynexis Inc. P.O.Box 12878 Research Triangle Park North Carolina 27709-2878 (US) (for US only)
PHILLIPS, Eifion [GB/US]; 27 John Beal Drive Bothwyn PA 19061 (US) (for US only)

(72) Inventor(s):
ERNST, Glen; AstraZeneca Wilmington P.O. Box 15437 Wilmington, Delaware 19850-5437 (US)
FRIETZE, William; AstraZeneca Wilmington P.O Box 15437 Wilmington, Delaware 19850-5437 (US)
JACOBS, Robert; Scynexis Inc. P.O.Box 12878 Research Triangle Park North Carolina 27709-2878 (US)
PHILLIPS, Eifion; 27 John Beal Drive Bothwyn PA 19061 (US)

(74) Agent(s):
ASTRAZENECA; Global Intellectual Property S-151 85 Södertälje (SE)

(54) Title (EN): NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS
(54) Title (FR): LIGANDS DES RECEPTEURS NICOTINIQUES DE L'ACETYLCHOLINE

(57) Abstract:
(EN): Acetylcholine receptor ligands of formula I wherein D, E and G are as described in the specification, diastereoisomers, enantiomers, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
(FR): L'invention concerne des ligands des récepteurs de l'acétylcholine de formule I, dans laquelle D, E et G sont tels que décrits dans la description, des diastéréoisomères, des énantiomères, des sels pharmaceutiquement acceptables, des méthodes de préparation, des compositions pharmaceutiques les contenant ainsi que des méthodes d'utilisation desdits ligands.

International search report:
Received at International Bureau: 22 April 2005 (22.04.2005) [SE]

International Report on Patentability (IPRP) Chapter II of the PCT:
Not available

(81) Designated States:
AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
European Patent Office (EPO) : AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR
African Intellectual Property Organization (OAPI) : BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG
African Regional Intellectual Property Organization (ARIPO) : BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW
Eurasian Patent Organization (EAPO) : AM, AZ, BY, KG, KZ, MD, RU, TJ, TM