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1. WO2020120466 - MIKROPHYSIOLOGISCHES CHOROIDEA-MODELL

Veröffentlichungsnummer WO/2020/120466
Veröffentlichungsdatum 18.06.2020
Internationales Aktenzeichen PCT/EP2019/084406
Internationales Anmeldedatum 10.12.2019
IPC
C12M 3/06 2006.01
CChemie; Hüttenwesen
12Biochemie; Bier; Spirituosen; Wein; Essig; Mikrobiologie; Enzymologie; Mutation oder genetische Techniken
MVorrichtungen für Enzymologie oder Mikrobiologie
3Vorrichtungen zur Kultur von Gewebe, menschlichen, tierischen oder pflanzlichen Zellen, oder von Viren
06mit Einrichtungen zur Filtration, Ultrafiltration, umgekehrter Osmose oder Dialyse
C12M 1/12 2006.01
CChemie; Hüttenwesen
12Biochemie; Bier; Spirituosen; Wein; Essig; Mikrobiologie; Enzymologie; Mutation oder genetische Techniken
MVorrichtungen für Enzymologie oder Mikrobiologie
1Vorrichtungen für Enzymologie oder Mikrobiologie
12mit Einrichtungen zum Sterilisieren, Filtrieren oder zur Dialyse
CPC
C12M 21/08
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
21Bioreactors or fermenters specially adapted for specific uses
08for producing artificial tissue or for ex-vivo cultivation of tissue
C12M 23/16
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
23Constructional details, e.g. recesses, hinges
02Form or structure of the vessel
16Microfluidic devices; Capillary tubes
C12M 25/02
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
25Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
02Membranes; Filters
C12M 25/14
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
25Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
14Scaffolds; Matrices
C12M 35/08
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
35Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
08Chemical, biochemical or biological means, e.g. plasma jet, co-culture
G01N 33/5011
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
5005involving human or animal cells
5008for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
5011for testing antineoplastic activity
Anmelder
  • FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. [DE]/[DE]
Erfinder
  • PROBST, Christopher
  • CIPRIANO, Madalena
  • LOSKILL, Peter
Vertreter
  • SCHWAHN, Hartmut
  • SCHRELL, Andreas
  • WOHLFAHRT, Jan
  • CLARENBACH, Carl-Philipp
  • KORDEL, Mattias
  • DIETZ, Christopher
  • KRÜGER, Torsten
  • HEIDE, Nils
  • DECKERS, Daniel A.
Prioritätsdaten
10 2018 221 838.214.12.2018DE
Veröffentlichungssprache Deutsch (DE)
Anmeldesprache Deutsch (DE)
Designierte Staaten
Titel
(DE) MIKROPHYSIOLOGISCHES CHOROIDEA-MODELL
(EN) MICROPHYSIOLOGICAL CHOROID MODEL
(FR) MODÈLE DE CHOROÏDE MICROPHYSIOLOGIQUE
Zusammenfassung
(DE)
Die Erfindung liegt auf dem technischen Gebiet der Kultivierung von biologischen Zellen und Geweben mit organähnlicher Funktion in mikrophysiologischem Maßstab und stellt eine mikrophysiologische Nachbildung der Aderhaut und Blut/Retina-Schranke als in vitro-Testsystem bereit.
(EN)
The invention relates to the field of cultivating biological cells and tissues having an organ-like function on a microphysiological scale and provides a microphysiological reproduction of the choroid and the blood-retinal barrier as an in vitro test system.
(FR)
L'invention se rapporte au domaine technique de la culture de cellules et tissus biologiques ayant une fonction semblable à un organe à l'échelle microphysiologique et fournit une reproduction microphysiologique de la choroïde et de la barrière sang-rétine en guise de système d'essai in vitro.
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