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1. (WO2018189124) METHOD FOR OBTAINING DIFFERENTIATED CELLS FROM MUSCLE DERIVED PROGENITOR CELLS



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INTERNATIONAL SEARCH REPORT (ISR)
Part 1:  1  2  3  4  5  6          Part 2:  A  B  C  D  E 
International application No. Applicant's or agent's file reference
PCT/EP2018/059061 B49297REVA3
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
09 April 2018 12 April 2017
Applicant
REVATIS SA
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
b.
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
c.
With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.
6. Drawings
a.
The figure of the drawings to be published with the abstract is Figure No. ____________
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
b.
none of the figures is to be published with the abstract.

A. CLASSIFICATION OF SUBJECT MATTER

     C12N 5/0775 (2010.01)i
According to International Patent Classification (IPC) or to both national classification and IPC

B. FIELDS SEARCHED

Minimum documentation searched (classification system followed by classification symbols):
     C12N
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, WPI Data, BIOSIS, EMBASE

C. DOCUMENTS CONSIDERED TO BE RELEVANT

Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
(1)
X
DEBORAH MERRICK ET AL, "Adult and Embryonic Skeletal Muscle Microexplant Culture and Isolation of Skeletal Muscle Stem Cells", JOURNAL OF VISUALIZED EXPERIMENTS,No. 43, 21 September 2010 (2010-09-21),
XP055377852
1-9
abstract
paragraph [0002]
paragraph [6.14]
Discussion
(2)
X
WO 2015091210 A1 (UNIV LIEGE [BE]) 25 June 2015 (2015-06-25)
1-9
cited in the application
claims 1-21
page 20, line 24; example 1
(3)
X
BURHAN GHARAIBEH ET AL, "Isolation of a slowly adhering cell fraction containing stem cells from murine skeletal muscle by the preplate technique", NATURE PROTOCOLS,Vol. 3, No. 9, 04 September 2008 (2008-09-04), page 1501-1509,
XP055377873
5-9
A
abstract
1-4
figure 2
table 1
(4)
X
ALESSANDRI G ET AL, "Isolation and culture of human muscle-derived stem cells able to differentiate into myogenic and neurogenic cell lineages", THE LA, THE LANCET PUBLISHING GROUP, GB,Vol. 364, No. 9448, 20 November 2004 (2004-11-20), page 1872-1883,
XP004769906
5-9
A
abstract
1-4
Methods;page 1873
(5)
X
WESLEY M JACKSON ET AL, "Potential therapeutic applications of muscle-derived mesenchymal stem and progenitor cells", EXPERT OPINION ON BIOLOGICAL THE, INFORMA HEALTHCARE, ASHLEY, LONDON; GB,Vol. 10, No. 4, 01 April 2010 (2010-04-01), page 505-517,
XP009177178
5-9
abstract
(6)
T
J. CEUSTERS ET AL, "From skeletal muscle to stem cells: an innovative and minimally-invasive process for multiple species", SCIENTIFIC REPORTS,Vol. 7, No. 1, 06 April 2017 (2017-04-06),
XP055377964
the whole document
(7)
A
PARVIN SALEHINEJAD ET AL, "Comparison of different methods for the isolation of mesenchymal stem cells from human umbilical cord Wharton's jelly", IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY - ANIMAL, SPRINGER-VERLAG, NEW YORK,Vol. 48, No. 2, 25 January 2012 (2012-01-25), page 75-83,
XP035018689
1-4
abstract
*
Special categories of cited documents:
"A"
document defining the general state of the art which is not considered to be of particular relevance
"E"
earlier application or patent but published on or after the international filing date
"L"
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
"O"
document referring to an oral disclosure, use, exhibition or other means
"P"
document published prior to the international filing date but later than the priority date claimed
"T"
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
"X"
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
"Y"
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
"&"
document member of the same patent family

D. INFORMATION ON PATENT FAMILY MEMBERS

Patent document cited in search report Publication date
(day/month/year)
Patent family member(s) Publication date
(day/month/year)
WO 2015091210 A1
25 June 2015
AU 2014365165 A1
CA 2934100 A1
CL 2016001510 A1
EP 3083944 A1
GB 2536366 A
HK 1222886 A1
JP 2017500860 A
US 2016186142 A1
WO 2015091210 A1
09 June 2016
25 June 2015
30 December 2016
26 October 2016
14 September 2016
14 July 2017
12 January 2017
30 June 2016
25 June 2015
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Netherlands
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
27 June 2018
Date of mailing of the international search report:
06 July 2018
Authorized officer:
Loubradou-Bourges, N
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