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1. (WO2018095877) I

Pub. No.:    WO/2018/095877    International Application No.:    PCT/EP2017/079835
Publication Date: Fri Jun 01 01:59:59 CEST 2018 International Filing Date: Wed Nov 22 00:59:59 CET 2017
IPC: C07D 213/74
C07D 401/12
C07D 405/12
C07D 409/12
A61K 31/4418
A61K 31/513
A61P 3/10
A61P 3/04
Inventors: ECKHARDT, Matthias
PETERS, Stefan
WAGNER, Holger
Title: I
The present invention relates to compounds of general formula (I), wherein the groups R, R1, R2, R3, m and n are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula (I).