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1. (WO2017013129) HER2 BINDING PROTEINS BASED ON DI-UBIQUITIN MUTEINS

Pub. No.:    WO/2017/013129    International Application No.:    PCT/EP2016/067207
Publication Date: Fri Jan 27 00:59:59 CET 2017 International Filing Date: Wed Jul 20 01:59:59 CEST 2016
IPC: C07K 16/32
C07K 14/47
C12N 15/62
Applicants: NAVIGO PROTEINS GMBH
Inventors: SETTELE, Florian
ZWARG, Madlen
GLOSER, Manja
BOSSE-DOENECKE, Eva
FIEDLER, Erik
HAUPTS, Ulrich
Title: HER2 BINDING PROTEINS BASED ON DI-UBIQUITIN MUTEINS
Abstract:
1Abstract The present invention relates to new Her2 binding molecules based on di-ubiquitin muteins. The invention further refers to Her2 binding proteins optionally fused or conjugated to a moiety modulating pharmacokinetics or to a therapeutically or diagnostically active component. The invention further relates to the use of these Her2 binding proteins in medicine, 5 preferably for use in the diagnosis or treatment of cancer.