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1. (WO2016139362) METHOD

Pub. No.:    WO/2016/139362    International Application No.:    PCT/EP2016/054714
Publication Date: Sat Sep 10 01:59:59 CEST 2016 International Filing Date: Sat Mar 05 00:59:59 CET 2016
IPC: A61K 39/00
A61K 39/12
A61K 39/39
A61K 47/48
A61K 41/00
C12N 5/0784
Applicants: PCI BIOTECH AS
Inventors: HØGSET, Anders
The invention concerns a method of generating an immune response in a subject, comprising administering to the subject an antigenic molecule, a photosensitizing agent, a checkpoint inhibitor, and irradiating said subject with light of a wavelength effective to activate the photosensitizing agent to generate an immune response. Preferably the method is a method of vaccination. The invention also provides related methods, compositions, cells, uses, products and kits.