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1. (WO2016046419) NEW IMMUNOSTIMULATORY COMPOUNDS

Pub. No.:    WO/2016/046419    International Application No.:    PCT/EP2015/072292
Publication Date: Fri Apr 01 01:59:59 CEST 2016 International Filing Date: Tue Sep 29 01:59:59 CEST 2015
IPC: A61K 31/683
A61K 31/7034
C07H 15/20
C07F 9/10
A61P 35/00
A61P 33/02
A61K 35/15
A61P 33/00
A61P 31/00
Applicants: BERNHARD-NOCHT-INSTITUT FÜR TROPENMEDIZIN
FORSCHUNGSZENTRUM BORSTEL
Inventors: LOTTER, Hannelore
BERNIN, Hannah
TANNICH, Egbert
GONZALEZ-ROLDAN, Nestor
FUJIMOTO, Yukari
FUKASE, Koichi
Title: NEW IMMUNOSTIMULATORY COMPOUNDS
Abstract:
The present invention relates to novel immunostimulatory molecules which are derived from the intestinal protozoan Entamoeba histolytica.The compounds have been found to be useful for enhancing and/or inducing an immune response in a subject in need thereof. Specifically, the compounds have been found to be useful for the treatment of cancer diseases, such as breast cancer, and parasitic diseases, such as leishmaniasis. The invention also provides pharmaceutical compositions comprising the novel compounds.