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1. (WO2002006510) PHOTOSELECTION OF NUCLEIC ACID LIGANDS

Pub. No.:    WO/2002/006510    International Application No.:    PCT/US2001/022561
Publication Date: Fri Jan 25 00:59:59 CET 2002 International Filing Date: Thu Jul 19 01:59:59 CEST 2001
IPC: C12Q 1/68
Applicants: SOMALOGIC, INC.
Inventors: GOLD, Larry
SMITH, Jonathan, Drew
KOCH, Tad
GOLDEN, Mace
Title: PHOTOSELECTION OF NUCLEIC ACID LIGANDS
Abstract:
Methods are described for the identification and preparation of high-affinity nucleic acid ligands to bFGF. Included in the invention are specific DNA ligands to bFGF identified by the photoSELEX method. Also included is a method for determining the position of a nucleic acid ligand - protein photoadduct.