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1. (WO1978000005) MAGNETIC POLYMER PARTICLES

Pub. No.:    WO/1978/000005    International Application No.:    PCT/SE1978/000001
Publication Date: Fri Dec 08 00:59:59 CET 1978 International Filing Date: Fri Jun 02 00:59:59 CET 1978
IPC: A61K 9/50
Applicants:
Inventors:
Title: MAGNETIC POLYMER PARTICLES
Abstract:
Magnetic polymer particles as carriers of biologically, preferably pharmaceutically active substance are produced. One process of producing the magnetic polymer particles is by treatment of a preferably porous polymer and/or polymerizable monomer with a colloidal solution of magnetic material, the magnetic material being deposited in the pores or lattice of the polymer. The active substance is associated with the polymer either before or after the magnetization. The substance can also be added to a mixture of monomer and magnetic material for deposition in the pores or lattice of the polymer together with the magnetic material at the polymerization. The produced particles can be used for local concentration of a medicine in an organism or for slow release from a deposit, the particles being retained by a magnetic field within a restricted area, and for example, in so-called affinity chromatography and immuno assays, such as RIA, ELISA.