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1. DK3592807 - FREMGANGSMÅDE OG MATERIALE TIL DIFFERENTIERET SEKVESTRERING AF STOFFER FRA FORSKELLIGE STOFGRUPPER VED HJÆLP AF HYDROGELER INDEHOLDENDE SULFATEREDE ELLER SULFONEREDE BESTANDDELE

Amt
Dänemark
Aktenzeichen/Anmeldenummer 18715886
Anmeldedatum 09.03.2018
Veröffentlichungsnummer 3592807
Veröffentlichungsdatum 13.09.2021
Erteilungsnummer 3592807
Erteilungsdatum 13.09.2021
Veröffentlichungsart T3
IPC
C08L 5/10
CSektion C Chemie; Hüttenwesen
08Organische makromolekulare Verbindungen; deren Herstellung oder chemische Verarbeitung; Massen auf deren Basis
LMassen auf Basis makromolekularer Verbindungen
5Massen auf Basis von Polysacchariden oder deren Derivaten, soweit nicht in den Gruppen C08L1/ oder C08L3/154
10Heparin; Derivate davon
C08L 25/08
CSektion C Chemie; Hüttenwesen
08Organische makromolekulare Verbindungen; deren Herstellung oder chemische Verarbeitung; Massen auf deren Basis
LMassen auf Basis makromolekularer Verbindungen
25Massen auf Basis von Homopolymerisaten oder Mischpolymerisaten von Verbindungen, die einen oder mehrere ungesättigte aliphatische Reste aufweisen, von denen jeder nur eine einzige Kohlenstoff-Kohlenstoff-Doppelbindung besitzt und wobei wenigstens einer mit einem endständigen aromatischen carbocyclischen Ring versehen ist; Massen auf Basis von Derivaten solcher Polymerisate
02Homopolymerisate oder Mischpolymerisate von Kohlenwasserstoffen
04Homopolymerisate oder Mischpolymerisate des Styrols
08Mischpolymerisate des Styrols
CPC
C08L 5/10
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
5Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
10Heparin; Derivatives thereof
C08L 2666/02
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
2666Composition of polymers characterized by a further compound in the blend, being organic macromolecular compounds, natural resins, waxes or and bituminous materials, non-macromolecular organic substances, inorganic substances or characterized by their function in the composition
02Organic macromolecular compounds, natural resins, waxes or and bituminous materials
C08B 37/0075
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
BPOLYSACCHARIDES; DERIVATIVES THEREOF
37Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
A61P 11/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
A61P 17/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
02for treating wounds, ulcers, burns, scars, keloids, or the like
A61P 19/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
02for joint disorders, e.g. arthritis, arthrosis
Anmelder Leibniz-Institut für Polymerforschung Dresden e.V.
Erfinder ATALLAH, Passant
FREUDENBERG, Uwe
SCHIRMER, Lucas
WERNER, Carsten
Prioritätsdaten 102017105195 10.03.2017 DE
Titel
(DA) FREMGANGSMÅDE OG MATERIALE TIL DIFFERENTIERET SEKVESTRERING AF STOFFER FRA FORSKELLIGE STOFGRUPPER VED HJÆLP AF HYDROGELER INDEHOLDENDE SULFATEREDE ELLER SULFONEREDE BESTANDDELE
Zusammenfassung
(EN) The invention relates to a method for the differentiated sequestration of substances of different substance groups A and B in a sulphated and/or sulphonated hydrogel and depletion of substances of substance group A from a biofluid while simultaneously releasing substances of substance group A or B from the sulphated and/or sulphonated hydrogel in a differential manner into the biofluid and/or the reduction of the bond of the substances of substance group B in the sulphated and/or sulphonated hydrogel. The sulphated and/or sulphonated hydrogel is selected from a group of hydrogels of Type 1, Type 2, Type 3 or Type 4, and the hydrogels consist of uncharged components and charged components. According to the invention, the charged components are characterized by a parameter, which is calculated from the number of sulphate and/or sulphonate groups per repeat unit divided by the molar mass of the repeat unit, for Type 1 of 0.0040-0.0060 mol/g, for Type 2 of 0.0025-0.0040 mol/g, for Type 3 of 0.0005-0.0025 mol/g and for Type 4 of 0.0040-0.0100 mol/g. The swollen hydrogels have a storage modulus of less than 20 kPa, and the properties of the swollen hydrogels have a concentration of sulphate or sulphonate groups in mmol/ml of 0.09 to 0.20 for Type1, of 0.05 to 0.18 for Type 2, of 0.01 to 0.12 for Type 3 and of 0.16 to 0.08 for Type 4. The concentration of substances of substance group A and of substances of substance group B in the biofluid is influenced by the selection of the type of hydrogels.