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1. CN101175482 - Abuse-proofed dosage form

Amt
China
Aktenzeichen/Anmeldenummer 200680011300.3
Anmeldedatum 06.02.2006
Veröffentlichungsnummer 101175482
Veröffentlichungsdatum 07.05.2008
Erteilungsnummer 101175482
Erteilungsdatum 18.09.2013
Veröffentlichungsart B
IPC
A61K 9/20
ASektion A Täglicher Lebensbedarf
61Medizin oder Tiermedizin; Hygiene
KZubereitungen für medizinische, zahnärztliche oder kosmetische Zwecke
9Medizinische Zubereitungen, charakterisiert durch besondere physikalische Form
20Pillen, Pastillen oder Tabletten
CPC
A61J 3/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
3Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
10into the form of compressed tablets
A61K 9/2031
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, tablets, ; discs, rods
2004Excipients; Inactive ingredients
2022Organic macromolecular compounds
2031obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
A61K 31/135
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines
135having aromatic rings ; , e.g. ketamine, nortriptyline
A61K 31/277
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
275Nitriles; Isonitriles
277having a ring, e.g. verapamil
A61K 31/4418
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non condensed pyridines; Hydrogenated derivatives thereof
4418having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
A61K 31/4422
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non condensed pyridines; Hydrogenated derivatives thereof
44221,4-Dihydropyridines, e.g. nifedipine, nicardipine
Anmelder 格吕伦塔尔有限公司
Erfinder J·阿什沃思
E·阿克诺-马里克
J·巴索洛莫斯
H·库格曼
Vertreter 中国专利代理(香港)有限公司 72001
中国专利代理(香港)有限公司 72001
Prioritätsdaten 102005005446 04.02.2005 DE
Titel
(EN) Abuse-proofed dosage form
(ZH) 抗破碎的缓释给药剂型
Zusammenfassung
(EN)
The invention relates to a form of administration comprising a physiologically effective substance (A); one or several optional physiologically acceptable adjuvants (B); a synthetic or natural polymer (C); and an optional natural, semisynthetic, or synthetic wax (D). Said form of administration is provided with a minimum breaking strength of 400 N while releasing the physiologically effective substance (A) at least partly in a delayed manner in physiological conditions.

(ZH)

本发明涉及一种包含生理学活性物质(A);一种和几种任选的生理学可接受辅料(B);合成和天然聚合物(C);和任选的天然、半合成和合成蜡(D)的给药剂型。所述给药剂型的最小破碎强度为400N,在生理条件下至少部分以缓释方式释放生理学活性物质。