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1. (WO2019003098) TOPICAL PHARMACEUTICAL COMPOSITION COMPRISING MICONAZOLE AND LULICONAZOLE OR SALTS THEREOF
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CLAIMS

A topical pharmaceutical composition comprising i) miconazole or salts thereof; ii) luliconzole or salts thereof; and iii) one or more pharmaceutically acceptable excipient.

The topical pharmaceutical composition according to claim 1, wherein concentration of miconazole or salts thereof ranges from 0.25% to 4% by weight of the composition.

The topical pharmaceutical composition according to claim 1 and 2, wherein concentration of miconazole or salts thereof is 2% by weight of the composition. The topical pharmaceutical composition according to claim 1, wherein concentration of luliconzole or salts thereof ranges from 0.05% to 2% by weight of the composition.

The topical pharmaceutical composition according to claim 1 and 4, wherein concentration of luliconzole or salts thereof is 1% by weight of the composition. The topical pharmaceutical composition according to claim 1, further comprising lauromacrogol and urea.

The topical pharmaceutical composition according to claims 1 and 6, wherein the concentration of lauromacrogol ranges from 0.1% to 5% by weight of the composition.

The topical pharmaceutical composition according to claims 1 and 6, wherein the concentration of urea ranges from 0.05% to 10%; by weight of the composition. The topical pharmaceutical composition according to claim 1, wherein one or more pharmaceutically acceptable excipient is selected from the group consisting of bases, solubilizing or emulsifying agent, preservative, antioxidant, gelling agent, thickening agent, humectant, adsorbent, permeation enhancer, opacifying agent, chelating agent, acidifying or alkalizing or buffering agent and vehicle.