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Results 1-10 of 934 for Criteria: Office(s):all Language:FR Stemming: true maximize
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NoCtrTitlePubDateInt.ClassAppl.NoApplicantInventor
1. WOWO/2005/063754 - TRIAZOLE DERIVATIVES AS VASOPRESSIN ANTAGONISTS14.07.2005
C07D 401/04
PCT/IB2004/004059PFIZER LIMITEDBRYANS, Justin, Stephen
Compounds of formula (I), or pharmaceutically acceptable derivatives thereof, wherein: V represents a direct link or -O-; Ring A represents an optionally substituted 5- to 7-membered saturated heterocyclic ring, or a phenylene group.

2. WOWO/2005/062955 - AGONIST ANTI-TRKC ANTIBODIES AND METHODS USING SAME14.07.2005
G01N 33/53
PCT/US2004/043435RINAT NEUROSCIENCE CORP.PONS, Jaume
The invention concerns agonist anti-trkC antibodies, polypeptides, and polynucleotides encoding the same. The invention further concerns use of such antibodies, polypeptides and/or polynucleotides in the treatment and/or prevention of neuropathies, such as sensory neuropathies, including taxol-induced sensory neuropathy, cisplatin-induced sensory neuropathy, and pyridoxine-induced sensory neuropathy.

3. WOWO/2005/063739 - NOVEL QUINOLINE DERIVATIVES14.07.2005
A61K 31/4709
PCT/IB2004/004151PFIZER INC.HONG, Yufeng
The invention relates to compounds represented by Formula (I): and to pharmaceutically acceptable salts or solvates of said compounds, wherein each of A, R3-8, X3, X5, m, and n are defined herein. The invention also relates to pharmaceutical compositions containing the compounds of Formula (I) and to methods of treating hyperproliferative disorders in a mammal by administering compounds of Formula (I).

4. WOWO/2005/060749 - SUBSTITUTED ARYLPYRAZOLES AS PARASITICIDAL AGENTS07.07.2005
C07D 231/38
PCT/IB2004/004193PFIZER LIMITEDBILLEN, Denis
This invention relates to a range of 1-aryl-4-cyclopropylpyrazoles in which there is at least one fluorine attached to the cyclopropyl ring, to compositions comprising such compounds, processes to their synthesis and their use as parasticides.

5. WOWO/2005/060665 - 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS07.07.2005
A61K 31/44
PCT/US2004/042321INCYTE CORPORATIONXUE, Chu-Biao
The present invention relates to 3-cycloalkylaminopyrrolidine derivatives of the formula 1: (wherein R1, R2, R3, R4, R5, R6, R7, X, Y and Z are as defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of chemokine receptors and more specifically as modulators of the CCR2 and/or CCR5 receptor. The compounds and compositions of the invention may bind to chemokine receptors, e.g., the CCR2 and/or CCR5 chemokine receptors, and are useful for treating diseases associated with chemokine, e.g., CCR2 and/or CCR5, activity, such as atherosclerosis, restenosis, lupus, organ transplant rejection and rheumatoid arthritis.

6. WOWO/2005/061497 - PYRIDO[2,3-D]PYRIMIDINE-2,4-DIAMINES AS PDE 2 INHIBITORS07.07.2005
A61K 31/00
PCT/IB2004/004013PFIZER PRODUCTS INC.BEYER, Thomas, Arthur
The invention provides compounds of formula (I) prodrugs thereof, and the pharmaceutically acceptable salts of the compounds or prodrugs, wherein n, X, and Y are as defined herein; pharmaceutical compositions thereof; combinations thereof; and uses thereof.

7. WOWO/2005/060963 - BENZENESULFONYLAMINO-PYRIDIN-2-YL DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 (11-BETA-HSD-1) FOR THE TREATMENT OF DIABETES AND OBESITY07.07.2005
A61K 31/44
PCT/IB2004/004056PFIZER INC.EDWARDS, Martin, Paul
The present invention relates to compounds with the formula (I), or a pharmaceutically acceptable salt thereof, wherein: R1 is selected from the group consisting of (C1-C6)alkyl, -(CR3R4)t(C3-C12)cycloalkyl, -(CR3R4)t(C6-C12)aryl, and -(CR3R4)t(4-10)-membered heterocyclyl; b and k are each independently selected from 1 and 2; j is selected from the group consisting of 0, 1, and 2; t, u, p, q, and v are each independently selected from the group consisting of 0, 1, 2, 3, 4, and 5; T is a (6-10)-membered heterocyclyl containing at least one nitrogen atom; R2 is selected from the group consisting of H, (C1-C6)alkyl, -(CR3R4)t(C3-C12)cycloalkyl, -(CR3R4)t(C6-C12)aryl, and -(CR3R4)t(4-10)-membered heterocyclyl; each R3 and R4 is independently selected from H and (C1-C6)alkyl, the carbon atoms of T, R1, R2, R3 and R4 may each be optionally, substituted by I to 5 R5 groups; R5 is defined in the claims; The compounds of the present invention are 11 ß-hsd-1 inhibitors, and are therefore believed to be useful in the treatment of diabetes, obesity, glaucoma, osteoporosis, cognitive disorders, immune disorders, depression, hypertension, and metabolic diseases.

8. WOWO/2005/058276 - PHARMACEUTICAL ORAL DOSAGE FORM COMPRISING A NON-STEROIDAL ANTI-INFLAMMATORY DRUG, AND HAVING GOOG PALATABILITY30.06.2005
A61K 9/00
PCT/EP2004/014465AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.MARCHITTO, Leonardo
Oral pharmaceutical dosage form comprising tromethamine and a NSAID selected from the group comprising ibuprofen, naproxen and flurbiprofen, characterized in that it also comprises a compound selected from the group comprising glycine, vitamine B6 and mixtures thereof.

9. WOWO/2005/054218 - NITROOXYDERIVATIVES OF ANTIHYPERTENSIVE DRUGS16.06.2005
C07D 285/10
PCT/EP2004/013682NICOX S.A.DEL SOLDATO, Piero
The present invention relates to β-adrenergic blockers nitrooxyderivatives of general formula (I): A-(Y-ONO2)s and enantiomers and diastereoisomers and pharmaceutically acceptable salts thereof, pharmaceutical compositions containing them and their use for the treatment of hypertension, cardiovascular diseases, glaucoma, migraine headache and vascular diseases.

10. WOWO/2005/052039 - METHOD FOR PRODUCING PET FILMS09.06.2005
B29C 39/14
PCT/EP2004/011231ZIMMER AGEHRHARDT, Werner
The invention relates to a method for producing PET films, according to which a poIyethylene terephthalate melt is transferred to a roller and the resultant film is drawn longitudinally. To produce the polyethylene terephthalate that is present in the melt, a branching agent is used in a concentration of between 50 to 300 ppm, in relation to the total weight of polyethylene terephthalate contained in the melt.


Results 1-10 of 934 for Criteria: Office(s):all Language:FR Stemming: true
préc. 1 2 3 4 5 6 7 8 9 10 suiv.