|1.||WO||WO/2014/141287 - THE ART, METHOD, MANNER, PROCESS AND SYSTEM OF MULTIFUNCTIONAL NANOBIOMATERIAL FOR MOLECULAR IMAGING AND DRUG- DELIVERY||18.09.2014||
|PCT/IN2013/000142||AMRITA VISHWA VIDYAPEETHAM UNIVERSITY||KOYAKUTTY, Manzoor|
The present invention relates to a nano-sized material that can provide contrast enhancement for multiple molecular imaging mthods and also deliver therapeutic nucleic acids or chemodrugs at a specific site of disease such as cancer. In particular, the present invention relates to a nanosized synthetic calcium apatite based materials showing contrast imaging for visible to near-infrared fluroscence, magnetic resonance imaging and x-ray imaging together with targeted delivery of nucleic acid drugs (DNA or RNA) to specific cancer types.
|2.||WO||WO/2014/141288 - THE ART, METHOD, MANNER, PROCESS AND SYSTEM OF A NANO-BIOMINERAL FOR MULTI-MODAL CONTRAST IMAGING AND DRUG DELIVERY||18.09.2014||
|PCT/IN2013/000143||AMRITA VISHWA VIDYAPEETHAM UNIVERSITY||KOYAKUTTY, Manzoor|
The present invention relates to a nano-sized material that can provide contrast enhancement for multple imaging methods and also deliver therapeutic molecules such as nucleic acids or chemo drugs to diseased sites such as cancer. In particular, the present invention relates to nano-sized synthetic calcium phosphates and calcium apatite nanomaterials showing simultaneous contrast for at least any two of the medical imaging modalities including radio, raman-, near-infrared fluroscence-, magnetic resonance and x-ray-imaging.
|3.||WO||WO/2014/141289 - PHOTO - CHEMO COMPOSITION ON THE BASIS OF MICROCAPSULES WITH A CORE -SHELL STRUCTURE||18.09.2014||
|PCT/IN2013/000144||AMRITA VISHWA VIDYAPEETHAM UNIVERSITY||MANZOOR KOYAKUTTY|
The present invention is related to a core-shell photo-chemo nanomedicine aiding sequential or simultaneous delivery of a photosensitizer drug and at least one chemotherapeutic drug for combinatorial photodynamic therapy and chemotherapy of cancer. The nanomedicine core is made up of a biodegradable or biocompatible polymer and the shell is either by polymer or a protein aiding the following two configurations; (i) polymer core-polymer shell and (ii) polymer core-protein shell. The core-shell nanomedicine is made in such a way that, while the core is loaded with photosensitizer, the shell will be loaded with a chemo-drug or vice-versa. Along with improving drug solubility, stability, bioavailability and therapeutic efficiency, the core-shell nanomedicine platform aids sequential or simultaneous delivery of photosensitizer and chemo drugs to cancer type diseases and thereby facilitates the application of photodynamic reactive oxygen stress together with or followed by chemotherapy. In addition, this core-shell nanomedicine can be targeted specifically to the disease site by conjugating with targeting molecules such as antibodies, peptides, small molecules, vitamins, proteins, etc. This core-shell photo-chemo nanomedicine system is capable of excreting photodynamic reactive oxygen stress together with or followed by chemotherapy.
|4.||WO||WO/2014/141296 - PROCESS FOR THE PREPARATION OF TAPENTADOL VIA NOVEL INTERMEDIATE||18.09.2014||
||PCT/IN2014/000151||IND-SWIFT LABORATORIES LIMITED||NAIK Rajesh Vinodrai|
The present invention relates to a commercially viable and improved process for preparation of tapentadol of formula I and its pharmaceutically acceptable salts, Formula I via novel intermediates tertiary hydroxy protected sulfonyl compound of formula III. Formula III wherein R1 is selected from hydrogen, straight chain or branched alky I, aryl, aralkyl, alkaryl which can be substituted or unsubstituted; and R2 represents CH3-CO-, CF3-CO-, CH2CICO-, CHCI2-CO-, CCI3-CO-, CH3O-CO-CO-, CH3O-CO-, CH3CH2O-CO-, CH3CH2O-CO-CO, phenyl-CO-, or meta-CH3COO-phenyl- CO- or -S02R'; wherein R' can be selected from hydrogen, straight chain or branched alkyl, aryl, aralkyl, alkaryl, heteroalkyl, heteroaryl and like which can be substituted or unsubstituted.
|5.||WO||WO/2014/141304 - PROCESS FOR THE PRODUCTION OF CYCLOSPORIN-A USING THE FUNGUS TOLYPOCLADIUM SP. STRAIN NRRL NO. :18950||18.09.2014||
|PCT/IN2014/000160||INDIAN COUNCIL OF MEDICAL RESEARCH||MANONMANI A. Mary|
This invention relates to a process for the production of Cyclosporin-A (Cyc-A) comprising the steps of inoculating a nutrient medium with the fungus Tolypocladium sp., strain NRRL No. 18950 followed by cultivation under static conditions to obtain a fermented medium with the fungal biomass, harvesting the biomass and subjecting the harvested biomass to extraction followed by purification to obtain pure Cyc-A, wherein said nutrient medium comprises glucose, glycerol, casein acid hydro lysate, malt extract, peptide, L-valine.
|6.||WO||WO/2014/141303 - ELECTRICAL CONNECTOR ASSEMBLY BEING USED FOR MULTIPLE CURRENT RATINGS||18.09.2014||
||PCT/IN2014/000159||RAVAL, Bhupendra Kantilal||RAVAL, Bhupendra Kantilal|
Present invention provides unique electrical connector assembly. The electrical connector assembly includes plugs which can be used for multiple current ratings of 2A and 6A. The invention further provides appertaining electrical receptacles which are compatible with the plugs of the present invention. Due to multiple current ratings the plugs are more reliable and usable. Furthermore multiple current ratings save material as well as cost to user.
|7.||WO||WO/2014/141305 - ATM (AUTOMATED TELLER MACHINE) MANAGEMENT SYSTEM-FOR INSTANT RESOLUTION OF CUSTOMER COMPLAINTS||18.09.2014||
||PCT/IN2014/000164||RAMANATHAN, NarayanaKumar||RAMANATHAN, NarayanaKumar|
The present invention relates to an ATM (Automated Teller Machine) Management System (AMS) for instant resolution of customer complaints with respect to cash transactions and a mechanism to provide instant access to ATM Electronic Journal (EJ), transaction images and more importantly root cause of failure. More particularly, the present invention relates to a transaction management part on the ATM comprising of an automatic transaction correlator part which is capable of doing multi-facet cash transaction failure analysis to arrive at the root cause of failure and give remedial hints towards resolving cash transaction disputes and transaction cash reconciliation, thereby reducing time to redress; a transaction failure notifier part in tandem with the transaction correlator part which segregates failure-only events, creates an intelligent fault-based failure-analysis record, notifies the same to central ATM Management System (AMS), thereby achieving a network bandwidth efficient transfer of failure-analysis records.
|8.||WO||WO/2014/141293 - A METHOD AND SYSTEM FOR ESTIMATION OF BLOOD ANYLATES||18.09.2014||
||PCT/IN2014/000138||SEN, ABHISHEK||SEN, ABHISHEK|
The present invention relates to a method and system for estimation of blood anylates, more particularly the invention relates to mitigation strategies for the confounding factors in the non-invasive estimation of blood anylates. The present invention is hypothesized to measured with an accuracy reasonable for an anaemia screening tool through measurement of the following parameters Finger Size, Transmitted infrared light through the finger, Finger tip temperature.
|9.||WO||WO/2014/141292 - ENDOXIFEN CITRATE POLYMORPH AND PROCESS FOR PREPARING THE SAME||18.09.2014||
||PCT/IN2014/000136||INTAS PHARMACEUTICALS LIMITED||DESAI, Sanjay Jagdish|
The present invention provides a novel crystal line form of Endoxifen citrate and process for preparation thereof.
|10.||WO||WO/2014/141301 - A MULTI-LAYER POLYMERIC FILM||18.09.2014||
||PCT/IN2014/000157||BILCARE LIMITED||KULKARNI SANJEEV DATTATRAY|
The present disclosure provides a multilayer formable barrier film having a thickness ranging from 100 to 750 micron comprising. The film comprises i) a substrate layer comprising a) a PVC film, optionally laminated with a PE film and, b) at least one layer of PVDC as a barrier layer; and ii) a base layer comprising a) a PVC film, optionally laminated with a PE film and, b) at least one layer of PVDC as a barrier layer, said base layer laminated to said substrate layer through an adhesive coat.