|1.||WO||WO/2014/049588 - A METHOD FOR TREATMENT OF PULMONARY FIBROSIS AND DIAGNOSIS OR PROGNOSIS OF AN AGGRESSIVE PULMONARY FIBROSIS PHENOTYPE||03.04.2014||
|PCT/IE2013/000020||UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN||DONNELLY, Seamas|
The invention relates to a method for the treatment of Pulmonary Fibrosis in a genetically distinct sub-cohort of human pulmonary fibrosis patients. The method comprises a step of administering a therapeutically effective amount of interferon-beta to a patient that is identified as carrying the C1234→T polymorphism in one or both alleles of the TLR-3 gene by assaying a biological sample from the patient for the presence of the polymorphism. Related aspects of the invention include diagnosis or prognosis of an aggressive phenotype of IPF or sarcoidosis or early mortality risk, stratification of pulmonary fibrosis patients according to need for a lung transplant, and selection of patients for participation in a clinical trial for a pulmonary fibrosis drug.
|2.||WO||WO/2014/045269 - APPARATUS AND A METHOD FOR PREVENTING UNAUTHORISED ACCESS TO AN ELECTRICAL PIN AND SLEEVE SOCKET CONNECTOR||27.03.2014||
|PCT/IE2013/000019||LAMBERT, Gerard, Patrick||LAMBERT, Gerard, Patrick|
An assembly (1) comprises a pin and sleeve socket connector (3) and apparatus (5) comprising a closure element (17) engageable with the pin and sleeve socket connector (3) for closing an open mouth (11) of a sleeve (9) of the pin and sleeve socket connector (3) to prevent unauthorised access thereto. The closure element (17) comprises a tubular element (19) defining a hollow interior region (23) which is closed at one end by an end cap (22) and terminates in its other end in an open mouth (24) to the hollow interior region (23). The tubular element (19) is engageable with the pin and sleeve socket connector (3) with a socket block (12) thereof extending through the open mouth (24) of the tubular element (19) into the hollow interior region (23) and with the forward portion (25) of the tubular element (19) located between the socket block (12) and the sleeve (9) of the pin and sleeve socket connector (3). Pincher elements (37) of a clasp (18) engage an eye bracket (33) of the tubular element (19) and embrace a hinge (16) of a closure cap (15) of the pin and sleeve socket connector (3) for securing the closure element (17) in the pin and sleeve socket connector (3). A padlock (45) secures and retains the clasp (18) in the closed state, thereby preventing unauthorised access to the pin and sleeve socket connector (3).
|3.||WO||WO/2014/041528 - A COMPOSITION||20.03.2014||
||PCT/IE2013/000018||MARTIN, Roslain Margaret||MARTIN, Roslain Margaret|
A composition which can be oral or topical for treating the cutaneous signs of ageing comprising collagen and a combination of Reactive Oxygen Species (ROS) scavengers/antioxidants such Vitamin C, disulfides, tocopherols/tocotrienols, carotenoids and coenzyme Q10 and collagen pre-cursors and use of such compositions for treating cosmetic ageing.
|4.||WO||WO/2014/030150 - A BALE WRAPPER AND A COMBINED BALER/BALE WRAPPER||27.02.2014||
|PCT/IE2013/000017||MCHALE ENGINEERING||HEANEY, James, John|
A combined baler/bale wrapper (1) comprises a baler (10) mounted on a chassis (5) and a bale wrapper (14) mounted on the chassis (5) rearwardly of the baler (10) for wrapping a bale formed by the baler (10). The bale wrapper (14) comprises a pair of first and second bale support rollers (50,51 ) for supporting and rotating the bale about a first wrapping axis (56). A pair of wrapping film dispensers (60) are carried on a carrier ring (58) which is rotated about a second wrapping axis (61) for dispensing wrapping film onto the bale (2) as the bale (2) is being rotated by the first and second bale support rollers (50,51). The first bale support roller (50) is carried on a transfer element (16) so that as the transfer element (16) is pivoted about a transfer pivot axis (17) from a first state to a second state for transferring the bale (2) onto the bale wrapper (14) the first bale support roller (50) is urged in a downwardly direction (F) in order to maximise the headroom available to the bale (2) as the bale (2) is being transferred by the transfer element (16) to the bale wrapper (14).
|5.||WO||WO/2014/024177 - AN ANIMAL BARRIER||13.02.2014||
|PCT/IE2013/000016||MURPHY, Neilus||MURPHY, Neilus|
Reference Fig 8 an animal barrier (5) is mechanically fixed to a pivot hub (9) which rotates in the vertical plane from a horizontal position, (closed position) to a vertical position, (open position) when the unit is activated via pre set timer or remotely by GSM mobile phone. The barrier is electrically connected to the nearby electric fence used to contain farm animals within an enclosed space making the barrier part of the fencing structure. For the purposes of operation, opening and closing and remote communication, the unit is powered by rechargeable battery. The unit is also portable and can be moved from post to post as required using the quick release and clamping ratchet (1).
|6.||WO||WO/2014/016818 - A WATER SAVING SYSTEM||30.01.2014||
|PCT/IE2013/000015||DOWLING, Jamie||DOWLING, Jamie|
A sanitary unit having a water inlet adapted to be sealably connected to the waste water pipe outlet pipe of a second sanitary unit, such that a secure connection seal is achieved between the inlet pipe of the sanitary unit and the outlet pipe of the second sanitary unit; and the sanitary unit is adapted to receive, as its water flushing supply, waste water from the second sanitary unit.
|7.||WO||WO/2013/164808 - A METHOD AND APPARATUS FOR TREATING HUMAN REMAINS BY CHILLING.||07.11.2013||
|PCT/IE2013/000013||ECOLEGACY LIMITED||TINSLEY, Damian|
A method of treating human remains prior to burial or other means of disposal comprises the steps of freezing the remains and size reducing the remains to particulate matter. The freezing step includes the steps of placing the remains in a freezing chamber, charging the chamber with a gas, and circulating the gas in a loop between the freezing chamber and a cooling device. The gas cooling device is adapted to cool the gas to a temperature below -100°C while maintaining the gas in a gaseous form.The gas cooling device may include a heatsink and a means for cooling the heatsink, wherein the circulating gas is cooled by being brought into contact with the heatsink.
|8.||WO||WO/2013/164809 - A METHOD AND APPARATUS FOR TREATING HUMAN REMAINS||07.11.2013||
|PCT/IE2013/000014||ECOLEGACY LIMITED||TINSLEY, Damian|
A process for treating a human remains comprises the steps of subjecting the remains to pyrolysis in a pyrolysis chamber under conditions that convert the particulate material to biochar remains.
|9.||WO||WO/2013/156986 - A BEDDING SYSTEM||24.10.2013||
|PCT/IE2013/000012||CASH, Bartholomew, Patrick||CASH, Bartholomew, Patrick|
An improved safety bedding system for a cot (2)comprising a multipurpose safety blanket for infants made up of a size adjustable blanket (1), an anchor fastenable to an anchor point (3) on the cot for holding the blanket in situ in the cot (2) and attachment means (4) for releasably attaching the blanket to the anchor, the blanket being held in situ in the cot to reduce the risk of suffocation and overheating of an infant.
|10.||WO||WO/2013/156985 - CEILING PLANK||24.10.2013||
|PCT/IE2013/000011||TOWER IPCO COMPANY LIMITED||STONE, Norman|
An elongated generally rectangular ceiling plank is formed of wood or plastic composition and has opposite elongated side edges with a length that is between nine and ten times the width of the opposite end edges. The ceiling plank includes complementary tongue and groove engagement portions formed at the sides and ends for side-by-side or end-to- end engagement with other similar planks. In a ceiling plank installation a ceiling plank securement clip secures the side groove portion of one plank to a ceiling. The secured plank can be joined to another plank in side-by-side or end-to-end engagement at a ceiling by interengagement with the tongue portion at the side or end of the other plank. The ceiling plank is approximately forty-eight inches long and five inches wide and can thus be easily handled and installed by one person.