||WO||WO/2014/142745 - PERMANENT MAGNET BASED HIGH PERFORMANCE MULTIAXIS IMMERSION ELECTRON LENS ARRAY WITH LOW AXIAL LEAKAGE FIELD||18.09.2014||
||PCT/SG2014/000102||LUO, Tao||LUO, Tao|
An apparatus includes a magnetic adjustment lens (116) positioned at the electron beam path between the electron source (102) and sample (124), the magnetic adjustment lens excited by an electric coil, and a permanent magnet lens (118) positioned below the magnetic adjustment lens to focus the electron beam onto the sample surface, the permanent magnet lens excited by one or more permanent ring magnets enclosed except on a bottom surface by a magnetic field conductor. The magnetic adjustment lens may be excited to eliminate magnetic field leakage of the permanent magnet lens.
||WO||WO/2014/142747 - POLYNUCLEOTIDE SEQUENCES FROM RHODOSPORIDIUM AND RHODOTOR ULA AND USE THEREOF||18.09.2014||
||PCT/SG2014/000114||TEMASEK LIFE SCIENCES LABORATOREY LIMITED||CHENG, Hsin I.|
The present invention relates to the application of isolated promoters and synthetic constructs for efficient production of genetically modified cells in a species selected from the Pucciniomycotina and Ustilaginomycotina subphyla, in particular, species selected from the Rhodosporidium, Rhodotourla, Sporobolomyces or Pseudozyma genus.
||WO||WO/2014/142761 - 3-PIPERIDONE COMPOUNDS AND THEIR USE AS NEUROKININ-1 (NK1) RECEPTOR ANTAGONISTS||18.09.2014||
||PCT/SG2014/000130||NANYANG TECHNOLOGICAL UNIVERSITY||LOH, Teck Peng|
The invention relates to 3-piperidone compounds, and in particular, to (2S)-phenyl-3-piperidone and its synthesis method. Use of the thus-synthesized 3-piperidone compounds as potent neurokinin-1 (NK1) receptor antagonists is also provided.
||WO||WO/2014/142756 - POLARIZED ELECTRODIALYSIS||18.09.2014||
||PCT/SG2014/000124||WISEWATER PTE. LTD||LIU, Haobing|
Some embodiments described herein generally relate to apparatus and methods for performing polarized electrodialysis, which may be used for desalination, purification and concentration. Such apparatus may include, for example, a pair of electrodes, a plurality of ion exchange membranes disposed between the pair of electrodes and a reservoir between each of the electrodes and the ion exchange membranes. The ion exchange membranes may include cation exchange membranes alternating with anion exchange membranes. A voltage may be applied between the pair of electrodes to generate concentration polarization wherein concentration of ions near the surface of one of at least one of the cation and anion exchange membranes is lower than a concentration of ions in the sample solution. The solution with lower ion concentration may be collected to form a desalinated stream by the apparatus. The apparatus and methods may also be able to remove or concentrate less mobile, weakly charged or bigger matters which cannot be purified by conventional electrodialysis.
||WO||WO/2014/142762 - COMBINED ULTRASONICATION AND ENZYMATIC PRETREATMENT OF WASTE ACTIVATED SLUDGE PRIOR TO ANAEROBIC DIGESTION||18.09.2014||
||PCT/SG2014/000131||NANYANG TECHNOLOGICAL UNIVERSITY||TRZCINSKI, Antoine Prandota|
There is herein disclosed a method of pretreating organic waste comprising the steps of (a) providing an organic waste; (b) subjecting the organic waste to ultrasonication; and (c) subjecting the ultrasonicated organic waste to a heat treatment step at a temperature of from 35°C to 85°C. There is also disclosed a waste treatment plant comprising a pre-treatment apparatus that comprises an ultrasonicator apparatus and a heating apparatus adapted to act in a batch or continuous fashion on an organic waste, wherein the ultrasonicator apparatus is placed upstream of the heating apparatus and is in fluid communication therewith.
||WO||WO/2014/142760 - RE-TRAFFICKING OF HERG REVERSES LONG QT SYNDROME 2 PHENOTYPE IN HUMAN IPS-DERIVED CARDIOMYOCYTES||18.09.2014||
||PCT/SG2014/000129||SINGAPORE HEALTH SERVICES PTE LTD||SHIM, Se Ngie, Winston|
The present invention relates to generating hiPSC-derived cardiomyocytes and embryoid bodies that recapitulate the disease phenotype of Long QT Syndrome and their use in developing pharmacological treatments thereof. The present invention also includes the use of a compound which inhibits the ubiquitin-proteasome pathway for the preparation of a medicament for the prophylaxis or treatment of a disease associated with prolonged ventricular repolarization (cardiac arrhythmia) caused by one or more mutations in the amino acid sequence of the hERG potassium channel.
||WO||WO/2014/142752 - PRE-ECLAMPSIA BIOMARKERS||18.09.2014||
||PCT/SG2014/000120||AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH||LIM, Sai Kiang|
We describe a method of detecting pre-eclampsia in a cell, tissue, organ or organism, the method comprising detecting a modulated level of expression, activity or amount of a pre- eclampsia biomarker polypeptide selected from the group consisting of P1GF, FLT1, BNP, ANP, CD9, PAI-1, TGF β, PCT, SI 00b, TIMPl, CD 105 and IL6 in or of a microparticle type (selected from a CTB binding microparticle and an Annexin V binding microparticle) from the cell, tissue, organ or organism, as compared to level of expression, activity or amount of the pre-eclampsia biomarker polypeptide in the same microparticle type in a cell, tissue, organ or organism not sufferin from pre-eclampsia.
||WO||WO/2014/142753 - SOLAR DEVICE WITH REMOVABLE CASSETTE||18.09.2014||
||PCT/SG2014/000121||THIRD WAVE POWER PTE LTD||LIM, Chuin Kiat|
Some embodiments described herein generally relate to a solar device with a removable cassette. The removable cassette is configured to dock with the solar device such that, in an engaged position, it may receive electrical energy generated from solar energy by a solar panel of the device, from internal batteries charged by the solar panel or an external power source. The cassette may include at least one of a battery and a power-consuming accessory, such as a wireless router, data storage, an output adapter, or the like. The internal batteries are configured to charge the cassette in cases where the solar panel is not generating electrical energy because of dim lighting or lack of lighting.
||WO||WO/2014/142758 - AN INTERACTIVE SYSTEM FOR VIDEO CUSTOMIZATION AND DELIVERY||18.09.2014||
||PCT/SG2014/000126||ROCKS INTERNATIONAL GROUP PTE LTD||STEPHAN, Karel Paul|
A method of displaying content is described, the method comprising the steps of defining a set of visual patterns and tagging metadata to the set of visual patterns. The method further comprises the steps of detecting the set of visual patterns within a digital image, wherein the detection of the set of visual patterns is robust to appearance variations caused by lighting changes, camera angle and partial occlusion; aggregating the tagged metadata with third party metadata; and displaying content along with the digital image, wherein the content is based on the aggregated metadata.
||WO||WO/2014/142759 - BATTERY PACK||18.09.2014||
||PCT/SG2014/000127||EV WORLD PTE LTD||CHOU, David T.|
A battery pack for a transport vehicle comprises a housing including output terminals for coupling with the electrical system; an energy storage pack to provide starting energy to the vehicle; a battery unit provided for power supply and starting energy to the vehicle; an energy storage unit for providing power supply to the energy storage pack when necessary; a charger unit to charge the energy storage pack or the energy storage unit; switches operable with the energy storage pack, battery unit, energy storage unit and charger unit and configured so that the battery unit operates between a normal, charging and jump start modes; a processor unit arranged for connection with the charger unit and the energy storage pack; means to activate a jump start mode wherein the switches are operable with the charger unit, the energy storage unit and the energy storage pack to provide starting energy to the battery unit.