|1.||WO||WO/2014/184797 - HEMOGLOBIN RECEPTOR AS NOVEL VACCINE FOR LEISHMANIASIS||20.11.2014||
|PCT/IN2014/000231||NATIONAL INSTITUTE OF IMMUNOLOGY||MUKHOPADHYAY, Amitabha|
The present invention in general relates Hemoglobin receptor or its part as a novel vaccine candidate against Leishmaniasis. Specifically, the present invention envisages HbR DNA for eliciting immune response in a mammal against Leishmaniasis. Additional aspect of the present invention is related to a vaccine composition for inducing immune response against Leishmaniasis in mammals. In a preferred aspect, the present invention relates to use of HbR-polypeptide as marker for diagnosis of Leishmania in kala-azar patients.
|2.||WO||WO/2014/184805 - BIOSENSOR FOR DETECTION OF MYCOTHIOL REDOX POTENTIAL||20.11.2014||
||PCT/IN2014/000316||INTERNATIONAL CENTRE FOR GENETIC ENGINEERING & BIOTECHNOLOGY||SINGH, Amit|
The disclosure provides a fusion construct that includes an engineered green fluorescent protein having a fluorescence spectrum that is sensitive to redox status and a mycothiol-dependent oxidoreductase linked to the engineered green fluorescent protein. The mycothiol-dependent oxidoreductase is a mycoredoxin identified from Mycobacterium tuberculosis strain H37Rv and the fusion construct can be used as a biosensor for detecting a change in a redox status of mycothiol in a cell.
|3.||WO||WO/2014/184803 - A PROCESS FOR REGENERATING IONIC COMPOUND||20.11.2014||
||PCT/IN2014/000253||RELIANCE INDUSTRIES LIMITED||ADURI PAVANKUMAR|
The present disclosure provides a process for regenerating the deactivated ionic compound. The process involves mixing a deactivated ionic compound with at least one solvent such as ethyl acetate and neutralizing with at least one base such as triethylamine and tert-butyl amine to obtain a precipitate. The obtained precipitate is filtered to obtain a residue which is then washed with a solvent such as dichloromethane to obtain the ionic compound.
|4.||WO||WO/2014/184810 - METHOD FOR ASSAYING GLYCATED PROTEIN||20.11.2014||
|PCT/IN2014/000331||COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH||CHOPRA, Adity|
The main objective of the present invention is to have a method for the detection of the percentage of glycated proteins, glycated hemoglobin/GA, in sample using a bifurcated column coupled with an electronic reader. The column consisting of two channels with one arm immobilized with affinity matrix specific for glycated region of the total protein. Another objective of the present invention is to make this device efficient, handy and operable in all kinds of field conditions.
|5.||WO||WO/2014/184809 - MODEL OF ALZHEIMER'S DISEASE||20.11.2014||
|PCT/IN2014/000330||COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH||BANDYOPADHYAY, Sanghamitra|
The invention features a non-transgenic rat model for early AD, using a metal mixture of As, Cd and Pb, characterized by enhanced synergistic amyloidogenicity in rat cortex and hippocampus. This model can serve as a tool for (a) AD-directed drug screening, and (b) determining mechanism of AD pathogenicity. It features induction of the A?-mediated apoptosis and induction of inflammation in rodent brain. The invention features novel astrocyte and neuronal cellular models for AD, using a metal mixture of As, Cd and Pb, characterized by enhanced synergistic amyloidogenicity. This model can serve as a tool for (a) AD-directed drug screening in astrocytes and neurons, and (b) determining mechanism of AD pathogenicity in cells. It features induction of the A?-mediated apoptosis and induction of inflammation in astrocytes and neurons.
|6.||WO||WO/2014/184804 - IONIC LIQUID COMPOSITION||20.11.2014||
||PCT/IN2014/000269||RELIANCE INDUSTRIES LIMITED||JAIN, Suresh Shantilal|
The present disclosure provides a composition for preparing aryl carboxylic acid; said composition comprising: at least one ionic liquid, at least one catalyst, at least one non-oxidizable polar solvent, and at least one oxidizable multi-alkylated arylene compound with no two successive ring positions bearing alkyl group. The present disclosure also provides a process for preparing aryl carboxylic acid.
|7.||WO||WO/2014/184808 - SPIRO-OXAZINES, INDOLINONES AND PREPARATION THEREOF||20.11.2014||
|PCT/IN2014/000327||COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH||THANKAPPAN, Biju Akkattu|
The present invention relates to novel spiro-oxazine analogues of Formula-I and Indolinone compounds of Formula-II or positional isomers, or stereoisomers, or derivatives, or pharmaceutically acceptable salt thereof. Formula-I Formula-II Further the invention provides transition- metal free multicomponent reaction (MCR) process for the preparation of said compounds of Formula-I and II using aryne precursor, N-substituted isatin and N-heteroaromatic compound as the nucleophile,under mild condition leading to formation of desired complex of spiro-oxazine analogues (I) and indolinone analogues (II) in high yield and selectivity.
|8.||WO||WO/2014/184798 - AN IMPROVED SYSTEM FOR MOUNTING HEATING PANELS ON TO WALL WITHOUT DRILLING HOLES ON THE WALL||20.11.2014||
|PCT/IN2014/000232||HBN AGENCIES||PATTABHI, V|
The invention relates to an improved system for Mounting Heating Panels on to wall without drilling holes on the wall, comprising at least one grooved vertical member to maintain a predetermined gap between the wall and the heating panel, the gap allowing natural convection of currents for heat transfer; a plurality of slots provided on upper portion of the vertical member enabling insertion of the heating panel; a plurality of spacers fixed on the wall using adhesive; wherein the top portion of the panel having at least two fixing holes, and wherein the vertical stand the upper portion of the panel are fixed to the wall via said plurality of spacers.
|9.||WO||WO/2014/184800 - SYSTEM AND METHOD FOR IMPLEMENTING HIGH AVAILABILITY OF SERVER IN CLOUD ENVIRONMENT||20.11.2014||
|PCT/IN2014/000237||ANAND, P. Ashok||ANAND, P. Ashok|
A system and method for implementing high availability of the server/nodes in a cluster of a cloud network. An application with respect to a customer/client can be received at a high availability manager of a cluster in a cloud network in order to assign the application to a server/node within the cluster. A seed server/node from a plurality of server/nodes within the cluster can be identified with respect to the application based on the application information and correlation identity of the customer. The seed server/node can be assigned with a primary server/node status in order to thereby communicate the cluster information with respect to the seed server/node to the plurality of server/node located within the cluster. A secondary server/node with respect to the application can be identified and assigned a secondary server/node status in order to thereby route the traffic of the seed server/node upon detecting a failure/alert is generated in order to effectively implement the high availability of server/nodes within the cluster of the cloud network.
|10.||WO||WO/2014/184801 - CRIME EVIDENCE PROVIDER CUM HELP SEEKER||20.11.2014||
||PCT/IN2014/000249||RAJAMANI, Muthuraj||RAJAMANI, Muthuraj|
The existing invention is crime evidence provider cum help seeker where the system is basically designed over cognitive model to give the machine the required intelligence of being situation aware of pervasive environment. The strength of the system will be in its design of integrating cognitive model with mobile and pervasive computing. For the communication part it uses well established mobile infrastructure. The system is composed of both hardware and software. This design gives the simplistic nature to the system further gives the hope it will comprehend the personal security of everyone by playing the role of presence of police informer cum help seeker, preventing crimes be happened. Without any doubt the system will pose heavy impact and trigger the development of e-governance projects in the departments associated with crime such as police, judiciary, forensic etc.