|1.||WO||WO/2014/122638 - THALIDOMIDE AND THALIDOMIDE ANALOGUES FOR THE STIMULATION IN HUMAN/ANIMALS OF STEM CELL FACTOR TO INCREASE REGENERATIVE POTENTIAL IN AGING CONDITIONS||14.08.2014||
|PCT/IE2014/000001||PRENDERGAST, Thomas, Patrick||PRENDERGAST, Thomas, Patrick|
The present invention relates to the administration of thalidomide and/or thalidomide analogues to a patient to enhance or maintain endogenous levels of stem cell factor in a patient to prevent and/or treat medical conditions associated with declining endogenous stem cell factor levels also known as mast cell growth factor or kit-ligand.
|2.||WO||WO/2014/097285 - SUSPENSION SYSTEM FOR THE FRONT WHEEL OF SINGLE-TRACK TWO- WHEELED VEHICLES NAMELY MOTORCYCLES AND BICYCLES.||26.06.2014||
|PCT/IE2013/000025||RAE, Robert||RAE, Robert|
A linkage front wheel suspension system for two-wheeled vehicles comprising of a control arm (4) hinged with the body (1) of the vehicle, fork member (2), and steering member (3). An upper ball joint (6) connects said steering member (3) to the body (1) of the vehicle and a lower ball joint (8) connects the outer end of said control arm (4) with said fork member (2). Fork member (2) extends upwards and rearwards from said lower ball joint (8) to hinge with said steering member (3). Steering member (3) extends upwards and forwards from this pivot point (10) to said upper ball joint (6). Means of steering control (5) connects with said steering member (3). Means of springing/dampening (9) connects with at least one of the said steering/suspension members. Said suspension system can utilise a lighter design of main frame, provide superior road-holding and can have reduced compression when front wheel braking.
|3.||WO||WO/2014/087391 - APPARATUS SECURING A LINER TO A BASIN AND A CORRESPONDING METHOD FOR WASHING A PATIENT||12.06.2014||
|PCT/IE2013/000026||CMC HYGEA LIMITED||MALONE, Michael|
Apparatus (1) for washing a bedridden patient comprises a basin (2) and a disposable water impermeable flexible liner (3) for lining a hollow interior region (12) of the basin (2). Retaining members (35) in retaining member accommodating recesses (37) located in corners (10) of the basin (2) engage engagement openings (30) formed in the liner (3) adjacent a peripheral upper edge (24) thereof and adjacent corners (27) of a peripheral wall (19) of the liner (3) for releasably securing and retaining the liner (3) to the basin (2). The basin (2) lined with the liner (3) is charged with water for washing the patient. On completion of washing, the liner (3) is removed from the basin (2) for disposal.
|4.||WO||WO/2014/080392 - AN EASEL AND A METHOD AND APPARATUS FOR PROTECTING AN ART WORK ON AN EASEL||30.05.2014||
|PCT/IE2013/000024||DILLON, John||DILLON, John|
An easel (1) for supporting an art work (2) comprising a cover (9) releasably and pivotally coupled to the easel (1 ) by partly hook-shaped tongue elements (49) which are engageable with a bar element (48) mounted on a transversely extending support ledge (43) of the easel (1). The cover (9) is pivotal about the bar element (48) between an open state illustrated in Fig. 1 exposing the art work (2), and a closed state illustrated in Fig. 5 secured to a tower element (22) of the easel (1) by a securing strap (69) for protecting the art work (2) on the easel (1). A rear protecting panel is provided behind the art work (2) on the easel (1) for protecting the rear of the art work (2).
|5.||WO||WO/2014/080391 - MODULAR INFLATABLE PERSONAL SHELTER||30.05.2014||
|PCT/IE2013/000023||HEALY, Ronan Patrick||HEALY, Ronan Patrick|
An arcuate inflatable modular personal shelter with flat sides having an inflatable mattress and an inflatable overhead internal frame upstanding therefrom covered with a shell- or tent-like canopy, the shelter being rapidly deployable in emergency situations, individual shelters also being adapted to mate with each other so that a plurality of personal shelters can be combined as required for multiple occupancy.
|6.||WO||WO/2014/076688 - A METHOD AND APPARATUS FOR DETERMINING THE QUALITY OF A BALL STRIKE BY A GOLF CLUB||22.05.2014||
|PCT/IE2013/000022||DUGGAN, Denis Michael||DUGGAN, Denis Michael|
Apparatus (1) for determining the quality of a ball strike by a golf club (2) comprises a glove (5) having a housing (8) located on the back (9) of the glove (5). A three-axis accelerometer (14) and a three-axis gyroscope (15) are located in the housing (8) for detecting acceleration and amplitude of vibration, respectively, of the golf club 2 in Z, X and Y axis directions. A microprocessor (30) reads signals from the accelerometer (14) and gyroscope (15) to determine the direction of movement of the golf club (2) prior to the ball strike, and the direction of vibrations in the golf club (2) after the ball strike. The quality of the ball strike is determined by the angular displacement between the direction of the vibrations in the golf club (2) just after the ball strike and the direction of movement of the golf club (2) just prior to the ball strike. A central illuminateable segment (25) of a visual display (23) is located on the housing (8) is illuminated to indicate a correct ball strike, llluminateable segments (24a to 24j) located on respective opposite sides of the central segment (25) indicate by how much the ball strike has been to one or other side of a correct ball strike, while lower and upper illuminateable segments (26, 27) indicate whether the ball strike was a "topped" ball strike or a "thinned" ball strike.
|7.||WO||WO/2014/064671 - A LIGHT BULB, A LIGHT BULB HOLDER, AND A COMBINATION OF A LIGHT BULB AND A LIGHT BULB HOLDER||01.05.2014||
|PCT/IE2013/000021||KOCHANSKI, Jerry||KOCHANSKI, Jerry|
A combination (110) of a light bulb (111) and a bulb holder (112) in which the light bulb (111) comprises a plurality of light emitting diodes (77) mounted on a mounting platform (76) located within a globe (74) of the light bulb (111). The mounting platform (76) is mounted on and in heat conducting engagement with a heat transfer member (75) which is located within and in heat conducting engagement with an Edison screw threaded first coupling element (73) also of heat conductive material, so that heat generated by the light emitting diodes (77) is conducted through the mounting platform (76), the heat transfer member (75) and the first coupling element (73) into the light bulb holder (112). The light bulb holder (112) comprises a body member (93) of heat conductive material having an internally Edison screw threaded socket (95) engageable with the first coupling element (73) of the light bulb (111). A plurality of heat exchange fins (97) extending outwardly from the body member (93) sink heat conducted from the light bulb (111) into the light bulb holder (112). Concentric contact elements (115,116) located at the end of the first coupling elements (73) are engageable with corresponding concentric first and second contact elements (121,122) located in the socket (95) for providing an electrical power supply to the light emitting diodes (77).
|8.||WO||WO/2014/049588 - A METHOD FOR TREATMENT OF PULMONARY FIBROSIS AND DIAGNOSIS OR PROGNOSIS OF AN AGGRESSIVE PULMONARY FIBROSIS PHENOTYPE||03.04.2014||
|PCT/IE2013/000020||UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN||DONNELLY, Seamas|
The invention relates to a method for the treatment of Pulmonary Fibrosis in a genetically distinct sub-cohort of human pulmonary fibrosis patients. The method comprises a step of administering a therapeutically effective amount of interferon-beta to a patient that is identified as carrying the C1234→T polymorphism in one or both alleles of the TLR-3 gene by assaying a biological sample from the patient for the presence of the polymorphism. Related aspects of the invention include diagnosis or prognosis of an aggressive phenotype of IPF or sarcoidosis or early mortality risk, stratification of pulmonary fibrosis patients according to need for a lung transplant, and selection of patients for participation in a clinical trial for a pulmonary fibrosis drug.
|9.||WO||WO/2014/045269 - APPARATUS AND A METHOD FOR PREVENTING UNAUTHORISED ACCESS TO AN ELECTRICAL PIN AND SLEEVE SOCKET CONNECTOR||27.03.2014||
|PCT/IE2013/000019||LAMBERT, Gerard, Patrick||LAMBERT, Gerard, Patrick|
An assembly (1) comprises a pin and sleeve socket connector (3) and apparatus (5) comprising a closure element (17) engageable with the pin and sleeve socket connector (3) for closing an open mouth (11) of a sleeve (9) of the pin and sleeve socket connector (3) to prevent unauthorised access thereto. The closure element (17) comprises a tubular element (19) defining a hollow interior region (23) which is closed at one end by an end cap (22) and terminates in its other end in an open mouth (24) to the hollow interior region (23). The tubular element (19) is engageable with the pin and sleeve socket connector (3) with a socket block (12) thereof extending through the open mouth (24) of the tubular element (19) into the hollow interior region (23) and with the forward portion (25) of the tubular element (19) located between the socket block (12) and the sleeve (9) of the pin and sleeve socket connector (3). Pincher elements (37) of a clasp (18) engage an eye bracket (33) of the tubular element (19) and embrace a hinge (16) of a closure cap (15) of the pin and sleeve socket connector (3) for securing the closure element (17) in the pin and sleeve socket connector (3). A padlock (45) secures and retains the clasp (18) in the closed state, thereby preventing unauthorised access to the pin and sleeve socket connector (3).
|10.||WO||WO/2014/041528 - A COMPOSITION||20.03.2014||
||PCT/IE2013/000018||MARTIN, Roslain Margaret||MARTIN, Roslain Margaret|
A composition which can be oral or topical for treating the cutaneous signs of ageing comprising collagen and a combination of Reactive Oxygen Species (ROS) scavengers/antioxidants such Vitamin C, disulfides, tocopherols/tocotrienols, carotenoids and coenzyme Q10 and collagen pre-cursors and use of such compositions for treating cosmetic ageing.