The present invention relates to the combination of memantine and baclofen active ingredients, and also to the method for achieving body weight loss and thereby treating obesity and related co-morbidities by co-administration of baclofen and memantine.

The subject of the invention is double pivot joint unit with running gear for road vehicles, which beneficially influences the turning ability and safety of the vehicle in a way that the turning lane is about half of the usual one, the swinging mass in the turn is significantly less, thereby the stability of the vehicle is significantly better. The joint unit (3) according to the invention is located between the front member (1) of the road vehicle and the rear member (2) of the vehicle, and the joint unit (3) has a structure consisting of rocker and linkages for preventing jack-knifing and for ensuring proportional turn, which is connected to the front member (1) of the vehicle and to the rear member (2) of the vehicle with rotating rings (4,5). It is characterised by that the joint unit (3) includes the intermediate axle (B) Or the vehicle or its twin axle (Bl, B2), or the twin axles (Bl, B2, B3, B4) of the intermediate joint units (3), and it has double pivots (13) along the longitudinal axis of the vehicle, and a structure that ensures proportional turn of the vehicle members.

The invention relates to concrete doped with glass fiber reinforced thermoset plastic waste, process for preparing the same and a lightweight dry concrete premix usable in said process.

Equipment for performing hydrotoxicological tests, having a chamber which is gas-tightly separated from the environment and contains a test tank eligible for liquid storage, above all there is a closeable opening which task is to help the placing in and out of the tank and ensures access to it, and the equipment contains at least two chambers (2) which are separated from each other by the help of gas tight plates (5) and each chamber (2) is able to receive several tanks (3); each chamber (2) has two gas tight sides (6) fixed to the truss (1a) of the equipment (1), front face (7), backside (9), gas tight top (10) and bottom parts (10a); ventilators (12) are inserted to the openings (11) of the sides (6); and the tank (3) is made of a single piece and closed by a removable cover (13) which contains blow-holes (14, 15). ˙

The invention relates to compounds of formula (I) and stereoisomers, tautomers and pharmaceutically acceptable salts thereof and processes for preparing them. In formula (I) X is -CH= or -N= or -N(R") -; Y is -N= or -N(R") -; R is an alkyl group, an aryl group or a heteroaryl group, which groups are unsubstituted or substituted; R' is hydrogen or PG1, R" is hydrogen or PG2, R"' is hydrogen or R'OCH2-; n is an integer of 1 to 3. The invention also relates to pharmaceutical compositions containing these compounds. The compounds according to the invention are glycogen phosphorylase inhibitors and can be used e.g. for the treatment of type 2 diabetes, cardiovascular disorders and tumorous growth.˙

The invention relates to toxin peptides capable of selectively inhibiting a Kv1.3 potassium channel protein. The toxin peptides of the invention are modified anuroctonus scorpion toxin peptides.˙

Illuminator for use in public lighting comprising LED devices (10) as light source, the LED devices (10) are mounted in printed circuit board (14) and have a light emitting end on the opposite side of the mounting. The light sources have a first plane (s) and perpendicular to it a second plane (0 with a respective first and second light emitting angle characteristic, the angle range of the first light emitting angle characteristic is wider than that of the second one. The illuminator has a weatherproof covering surface (13) in the direction of light emission, and the LED devices (10) are encompassed at least in the directions of light emission with a transparent dome-shaped covering (12) or covering portion (12') inserted in the weatherproof covering surface (13). Placed before the light emitting end of the LED devices (10) optical beam forming elements (11) having a double bulge are provided.

The invention relates to a snow removal apparatus (1) for preventing snow accumulated on a roof structure (9) from adhering to the roof surface. The invention is characterised by that it is implemented as consisting of a mesh structure (4) stretched between two tensioning elements (2, 3) secured to the outer surface of the roof structure (9) with securing elements (5), weight sensors (6) disposed on the mesh structure (4), and a switching element or switching elements (7), where the switching elements (7) are connected to a power source (10) through a transformer (12) and are operated by the weight sensors (6).

The invention relates to a method for the preparation of composite silica alcogels, aerogels and xerogels, comprising i) providing a reaction mixture comprising at least the following: - silane reagent, - base catalyst, - gelation retarding additive, - aqueous/organic solvent mixture, - guest particle, ii) agitating the reaction mixture as necessary and sufficient until achieving the viscosity where the spontaneous movement of the guest particles does not occur anymore; and iii) shaping the material obtained to a desired shape during or after step ii); then iv) drying, if desired The method according to the invention is also useful in continuous manufacturing technology, and the invention provides an apparatus for applying the method. The invention further provides novel composite silica alcogels, aerogels or xerogels obtainable by the method according to the invention.

The invention refers to primycin or a primycin component or a combination of primycin components, for use in the treatment or prevention of infections caused by Gram-positive bacteria resistant to methicillin and/or vancomycin and/or mupirocin or by penicillin-resistant streptococci. The invention also covers antibotic compositions containing these active agents.