|1.||WO||WO/2013/027182 - CAPSULE FOR LOCAL THERAPY BY MEANS OF AN ENDOLUMINAL PLASTER IN THE GASTROINTESTINAL SYSTEM||28.02.2013||
|PCT/IB2012/054239||SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA||PENSABENE, Virginia|
The present invention refers to the field of local therapies in the gas trointestinal system. In particular, it refers to a swallowable capsule for local therapy at a target site, said capsule comprising a capsule body with a longitudinal axis and equipped with image sensor means, said capsule further comprising a driving and orienting wireless system adapted to interact with an external unit for receiving information and the driving of said capsule, wherein said capsule comprises a compartment formed in said capsule body, said compartment housing a polymeric film means, said capsule also comprising supporting and releasing means for moving said polymeric film means according to a direction of application perpendicular to said longitudinal axis, from a retracted position where said polymeric film means are contained inside said compartment, to an extracted position where said polymeric film means is projected from said compartment to make contact with said target.
|2.||US||20120306114 - PROCESS FOR PREPARING BIOCOMPATIBLE FREE-STANDING NANOFILMS OF CONDUCTIVE POLYMERS THROUGH A SUPPORT LAYER||06.12.2012||
|13528798||GRECO Francesco||GRECO Francesco|
A process for the preparation of nanofilms of conductive polymers is described. The process comprises forming support layers comprised of various polymers and free-standing nanofilms can be obtained thereby. The nanofilms obtained by the process can have characteristics such as strength, flexibility, ability to adhere to different substrates, and biocompatibility, which can make them suitable for numerous different technological applications, and in particular applications in the biomedical field.
|3.||WO||WO/2012/164517 - ROBOTIC PLATFORM FOR MINI-INVASIVE SURGERY||06.12.2012||
|PCT/IB2012/052739||SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA||VALDASTRI, Pietro|
Robotic platform for mini-invasive surgery comprising robotic arms (4a, 4b) suitable to be placed in the body of a patient, introduced through a single access port, which are an extension of external robotic manipulators (19). The continuity between external (1) and internal (4a, 4b) robotic arms is guaranteed by means of a trans- abdominal magnetic connection (6) between the internal robotic arm integral with the external one. The trans-abdominal magnetic coupling not only guarantees a stable anchoring, but most of all it transfers degrees of freedom to the internal robotic arms, inducing the motion of internal magnets by means of the automatized motion of external magnets. It is also possible to reposition the internal robotic arms without requiring having to additionally perform incisions on the abdomen. Using the external robotic arms allows translating the internal ones on the entire abdomen thus providing a working space not bound to the point of insertion and theoretically unlimited.
|4.||WO||WO/2012/080947 - MAGNETICALLY GUIDED ROBOTIC DEVICE FOR ENDOSCOPIC PROCEDURES||21.06.2012||
|PCT/IB2011/055636||SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA||VALDASTRI, Pietro|
An endoscopic device of the capsular type that is mobile and that can be oriented inside a body cavity, such as the gastrointestinal tract, through a magnetic coupling of the inner magnetic means (1 1 ) inside said body and means for generating a magnetic field (13) external to the patient, and a system for blowing (4, 5, 6) a gaseous fluid and sucking said fluid and/or material present in the body cavity. The device is designed to avoid both the drawbacks of the conventional flexible endoscopes, by reducing the invasiveness and the pain, thus increasing the patient's compliance, and the drawbacks of the capsular endoscopes, by improving their ability to control the movement and keeping the dimensions small. The endoscopic device further allows to carry out local therapeutic and/or surgical treatments of areas of the inspected gastrointestinal tract.
|5.||WO||WO/2012/070016 - PROCESS FOR THE PREPARATION OF BIOCOMPATIBLE, FREE-STANDING NANOFILMS OF CONDUCTIVE POLYMERS||31.05.2012||
|PCT/IB2011/055288||SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA||GRECO, Francesco|
The invention concerns a process for the preparation of nanofilms of conductive polymers, through the formation of support layers of other polymers. The present process has advantageous properties such as cost-effectiveness, speed of execution and use of relatively simple instruments; and it also allows to obtain free-standing nanofilms, i.e. nanofilms that are stable and able to support themselves without the need for any support. The present nanofilms al so have further advantageous characteristics, such as strength, flexibility, ability to adhere to different substrates, and high biocompatibility, which make them suitable for numerous different technological applications, in particular in the biomedical field.
|6.||US||20120121712 - CELLULAR ELECTRIC STIMULATION MEDIATED BY PIEZOELECTRIC NANOTUBES||17.05.2012||
|13264158||Ciofani Gianni||Ciofani Gianni|
Piezoelectric nanotransducers for use in an in vivo treatment of cell stimulation through electrical stimulation are described. The nanotransducers are localized in a target site, and an electrical stimulus is induced in the same site through external stimulation of the nanotransducers by ultrasonic waves.
|7.||WO||WO/2012/035157 - MAGNETIC LEVITATION ENDOSCOPIC DEVICE||22.03.2012||
|PCT/EP2011/066149||SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA||SIMI, Massimiliano|
Endoscopic system, comprising an endoscopic device 1 moved by a magnetic levitation system comprising a first 2 and a second 3 module connected by means of a flexible joint 4 and each bearing one or more permanent magnets 21, 22, 31, 32, the second module 3 further being provided with a motor 34 for the actuation of the internal magnets 31, 32 thereof; and means 61, 62, 7 for generating a first and a second external magnetic field, adapted to respectively interact with the magnets of the first and of the second module with the aim of producing a desired magnetic field surrounding the second module 3 for an efficient working of the levitation system in orienting the second module 3 with respect to the first module 2.
|8.||WO||WO/2012/028557 - SWALLOWABLE CAPSULE FOR INSUFFLATION OF GASTROINTESTINAL TRACT||08.03.2012||
|PCT/EP2011/064764||SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA||VALDASTRI, Pietro|
A system for insufflating a body cavity comprising a swallowable capsule comprising a chamber (11) containing a fluid capable to generate biocompatible gas or vapour by phase transition or chemical reaction, the chamber (11) being formed with at least one orifice (7) for placing it in communication with the outside. The orifice (7) is blocked by a shutter (4, 6; 26) made of magnetic material and there are provided elastic means (8) able to generate an elastic force sufficient to keep said shutter sealingly engaged in the orifice. The system further comprises magnetic actuating means (12; 34) external to the body cavity for generating a magnetic force having strength sufficient to overcome the elastic force of the elastic means disengaging the shutter from the orifice.
|9.||WO||WO/2012/011132 - SYSTEM FOR CONTROLLED ADMINISTRATION OF A SUBSTANCE FROM A HUMAN-BODY-IMPLANTED INFUSION DEVICE||26.01.2012||
|PCT/IT2010/000319||SCUOLA SUPERIORE Dl STUDI UNIVERSITARI E Dl PERFEZIONAMENTO SANT'ANNA||RICOTTI, Leonardo|
A system for the controlled administration of a substance by means of an infusion device implanted in the human body comprising an implantable unit (200) for detecting a shortage or an excess of such substance or a physiological parameter correlatable to the shortage or excess of such substance, an infusion group of this substance (100) implantable in the peritoneal cavity and comprising a central control unit (105) for processing data received from the detection unit (200) in order to generate command signals for the release of the substance in the intraperitoneal cavity, energy storage means (106) to power said infusion group (100). The system also comprises a carrier of said substance (500) adapted to be ingested in order to passively reach the duodenal lumen, made of perforable material resistant to gastric acids and with parts in magnetizable metal, and a refilling device (103) for refilling the infusion group (100) with said substance, comprising a magnetic reversible docking group (113) for said carrier (500), facing the duodenal lumen and actuable when said carrier reaches a predetermined distance therefrom, and means (120) for drawing the substance from said carrier communicating with suction means (110) of said infusion group (100).
|10.||WO||WO/2011/135503 - ROBOTIC APPARATUS FOR MINIMALLY INVASIVE SURGERY||03.11.2011||
|PCT/IB2011/051772||SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA||SCARFOGLIERO, Umberto|
A robotic arm (101, 102; 201, 202) especially suited for laparoscopic surgery, comprising a torsional joint (6) and a flexural joint (5) serially arranged, said joints (5, 6) providing respective degrees of freedom for said arm, the robotic arm receiving drive means (38, 39) for said flexural (5) and torsional (6) joints. The robotic arm further comprises transmission means (340, 350, 34-36) placed between the drive means (38, 39) and the joints (5, 6). The transmission means comprise a first (340) and a second (350) assembly of three gear wheels, preferably of the conical type, and a train of three additional gear wheels (34-36) preferably straight-cut gear wheels, which couple the first (340) and second (350) assembly to form a differential mechanism.