||WO||WO/2013/058409 - SUSTAINED-RELEASE PREPARATION||25.04.2013||
||PCT/JP2012/077662||TAKEDA PHARMACEUTICAL COMPANY LIMITED||TANOUE, Yutaka|
Provided is a sustained-release preparation containing pioglitazone or a salt thereof as an active ingredient and showing superior sustainability. A sustained-release preparation containing pioglitazone or a salt thereof, which shows a dissolution ratio of pioglitazone of average 25-58% at the 2-hour time point, and average 60-100% at the 4-hour time point, in a dissolution test according to the 50 rpm USP Paddle Method and using pH 2.0 KC1/HC1 buffer at 37°C as a test solution.
||WO||WO/2013/055219 - UREA FINISHING METHOD||18.04.2013||
||PCT/NL2012/050715||STAMICARBON B.V.||MENNEN, Johannes Henricus|
Disclosed is a method for urea finishing. A urea solution is subjected to crystallization and, other than in conventional processes, the urea crystals are shaped by exerting mechanical force onto them. Thus, the conventional prilling or granulation finishing steps can be avoided, and so are the corresponding emissions of ammonia and/or dust. The crystallization comprises a flash crystallization. The invention also pertains to the urea particles obtainable by the process, to a urea plant, and to a method of modifying an existing urea plant.
||WO||WO/2013/050882 - EQUIPMENT FOR STRUCTURIZATION AND POLARIZATION OF FUEL, COMBUSTION MIXTURE OR WATER||11.04.2013||
||PCT/IB2012/002851||KUREGYAN, Kamo||KUREGYAN, Kamo|
The invention relates to engine construction, to equipment for improving fuel and combustion mixture. Also may be used for water processing. Economy of fuel and decrease of noxious air emissions in the atmosphere are achieved. Equipment for structurization and polarization of fuel, combustion mixture or water, comprises a body in a form of a hollow cylinder with a smooth inside surface and a rod mounted in the body, both made of current-conducting materials and connectable to the electric circuit. The equipment is supplied with a battery of current-conducting discs interleaved with insulating ones, positioned on the rod. The size of a working gap for passing fuel between the tops of the discs and the body doesn't exceed 1/10 of the size of the working surface of the body. The body and the rod are made of duralumin alloy, but the current-conducting discs of aluminum. The plain surfaces of the current-conducting discs are performed with electro insulating cover, without covering the tops of the discs.
||WO||WO/2013/050137 - A METHOD OF RECOVERING A DEPOSIT FROM THE SEA BED||11.04.2013||
||PCT/EP2012/004127||MARINE RESOURCES EXPLORATION INTERNATIONAL B.V.||PATRICIU, Dan Costache|
A method of recovering a deposit from the sea bed using a surface vessel (20) untethered from the sea bed and first and second suction vehicles (27; 30) which traverse the sea bed to suck up the deposit and are each connected to the surface vessel by a respective flexible riser (26; 29) along which a slurry of the deposit is transferred from the suction vehicles to the surface vessel. The method comprises moving the first and second suction vehicles to and fro across the sea bed in a plurality of lanes such that they travel substantially further than the surface vessel, turning or reversing each vehicle at the end of each lane in a manner such that the lanes are adjacent to one another to mine the deposit substantially without gaps between adjacent lanes. Only the suction vessels rest on the sea bed.
||WO||WO/2013/050136 - SUCTION MOUTH FOR A SUBSEA MINING TOOL||11.04.2013||
||PCT/EP2012/004126||MARINE RESOURCES EXPLORATION INTERNATIONAL B.V.||PATRICIU, Dan Costache|
A suction mouth (10) for mounting on the front of a subsea mining tool and to be pushed into sediment. The suction mouth comprises a hollow body (12) having an entrance opening (14) and an exit opening (16), wherein the body converges from the entrance opening towards the exit opening. The entrance opening has a lower lip (20) and an upper lip (22), and the upper lip comprises an extension (22a) projecting forwardly and upwardly relative to the lower lip to form a canopy over the entrance opening. The suction mouth (10) may include a valve (30) on the body downstream of the entrance opening which is operable to selectively provide a further entrance opening into the body. Where such a valve is present, the consistency of the material sucked in can be regulated.
||WO||WO/2013/045031 - COMPOSITION TO BE APPLIED TO THE SKIN, AND USE THEREOF||04.04.2013||
||PCT/EP2012/003802||ALNAPHARM GMBH & CO. KG||NAHAVANDI, Ali|
The present invention concerns a composition to be applied to the skin, which comprises a dermatologically compatible vehicle, coconut oil, hazelnut oil and/or avellana oil, and stinging nettle oil, as well as use thereof for the treatment of skin diseases.
||WO||WO/2013/047568 - INHIBITOR FOR CORNEAL EPITHELIAL CELL DEATH, INHIBITOR CHARACTERIZED BY COMBINING HYALURONIC ACID AND FLAVIN ADENINE DINUCLEOTIDE||04.04.2013||
||PCT/JP2012/074663||SANTEN PHARMACEUTICAL CO., LTD.||SAKAMOTO, Asuka|
An inhibitor for corneal epithelial cell death induced by ultraviolet irradiation and/or dryness, the inhibitor dramatically inhibits the decline of the number of living cells in corneal epithelial cells induced by ultraviolet irradiation or dryness as a result of combining hyaluronic acid or a salt thereof with flavin adenine dinucleotide or a salt thereof.
||WO||WO/2013/042006 - PYRROLOPYRIMIDINE AND PURINE DERIVATIVES||28.03.2013||
||PCT/IB2012/054702||PFIZER INC.||CHENG, Hengmiao|
The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Q, T, V, W, X, Y, Z, ring A, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17 and m are defined herein. There novel pyrrolopyrimidine and purine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
||WO||WO/2013/043085 - (RS)-2-(2-OXO-4-PHENYLPYRROLIDIN-1-YL)ACETAMIDE COMPOUND WHICH EXHIBITS MODULATORY ACTIVITY WITH A COMMENSURATE EFFECT, PHARMACEUTICAL SUBSTANCE (VARIANTS) AND USE THEREOF, COMPOSITION (VARIANTS)||28.03.2013||
||PCT/RU2012/000773||AKHAPKINA, Valentina Ivanovna||AKHAPKINA, Valentina Ivanovna|
The invention relates to various fields of medicine, pharmaceutics and pharmacology and the chemical pharmaceutical, pharmaceutical and parapharmaceutical industry, and specifically concerns a novel class of agents which exhibit modulatory activity with a commensurate effect. The essence of the invention is that the proposed (RS)-2-(2-oxo-4-phenylpyrrolidin-1-yl)acetamide product does not contain biologically inert substances which exert a negative effect on its newly discovered or significantly improved known properties and characteristics, giving rise to hitherto unknown fundamental and highly important ideas about the compound, expanding the scope of use thereof with an increase in the effectiveness and safety of use and an increase in the therapeutic index, and making it possible to produce the product and related products with the newly found properties and characteristics.
||WO||WO/2013/040478 - HYR1-DERIVED COMPOSITIONS AND METHODS OF TREATMENT USING SAME||21.03.2013||
||PCT/US2012/055604||LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER||IBRAHIM, Ashraf, S.|
The disclosure features isolated polypeptides of Hyr1. The disclosure further features vaccines and antibodies useful in treating or preventing candidiasis or Acinetobacter infections or both. Further disclosed are isolated polypeptides consisting of between 14 and 20 amino acids for vaccine preparation. The specific amino acid sequences of isolated polypeptides of Hyr1 are also disclosed.