Disclosed are processes towards Cabazitaxel (I) starting from 10-Deacetylbaccatin (III) that involve steps of either 7-OH monosilylation (passing through formula V) or 7,13-disilylation (passing through formulae XI, XII). Isopropanol Solvates of Cabazitaxel and processes to make this are also described.

The invention discloses a novel process for preparation of dexmedetomidine in higher yield and with enantiomeric purity more than 99%.

A perpetual motion gravity & buoyancy engine consists of two wheels (4), two shafts (10), 2n number of capsules (1) with/without an airbag, a belt (5), shaft less dumbbell shape pistons (3) with/without a valve, a flywheel (11), and flexible pipes (8). The two wheels (4) are provided on the two shafts (10) with particular distance and connected with the belt (5). The flywheel (11) is connected with an upper side shaft which is further connected with a generator or gearbox (6). The shaft less dumbbell shape pistons (3) with the valve are provided inside the cylindrical shape capsules (1) which can move up and down by gravitational force with the valve. The generator or the gearbox (6) is provided between the two wheels (4). One end of the 2n number of capsules (1) is open and the other end is connected with the flexible pipe (8). The front side of the first capsule is connected with the front side of the second capsule through the flexible pipe (8). An air compressor (7) is provided to blow out the air to accelerate the circulation speed of the capsules.

The invention pertains to a method and apparatus for separation of seeds from fruit pulp/skin/twigs, in general, coming out from juice producing industry as a waste and in particular from apple pomace. The method involves addition of apple pomace and water in a particular ratio to a vessel (1), mixing with an agitator (6,8) at optimum rpm for sufficient period, allowed to stand followed by secondary agitation. Based on difference in bulk density, seeds were separated from pomace. The seedless pomace withdrawn from horizontal (13) or inclined (14) outlets and seeds collected in seed collection chamber were removed through bottom valve (11). The seed trap (15) provided at inclined outlet (14) helps in their retention in the vessel (1). The seedless pomace is recovered by filtration from water. This spent water can be recycled for few times and then purged. Easy to handle separation device is energy efficient, compactly designed and can be used to separate the seeds efficiently up to 97%.

A self-sustainable zero influent and zero discharge waste to energy system and method for treating sugar factory effluent, press mud, and distillery spent wash, said system comprises: first Biomethanation and Anaerobic Digestion Module adapted to receive sugar factory effluent, press mud, and reverse osmosis reject water for obtaining biogas and organic digestate; second Biomethanation and Anaerobic Digestion Module adapted to receive distillery spent wash and liquid filtrate from Micro Strainer for obtaining biogas and dilute organic liquid effluent digestate; Biogas Cleanup Module for converting hazardous hydrogen sulphide in the biogas into elemental sulphur, and moisture-free Dry biogas; Biogas Engine Generator Module for producing electrical power, hot exhaust gas and hot water; Biogas Engine Exhaust Gas Waste Heat Recovery Module for producing Steam, and cooled exhaust gas for expulsion into atmosphere; Solid Fuel Module for producing solid fuel for a co-generation plant, liquid filtrate from Micro strainer for said second Biomethanation and Anaerobic Digestion Module; Hot condensate water from Solid Fuel Dryer returned in close loop to said Biogas Engine Exhaust Gas Waste Heat Recovery Module for producing steam; and Reverse Osmosis Waste Water Treatment Module for obtaining filtered effluent for reverse osmosis unit which outputs a first predefined portion of reverse osmosis, usable water and a second remainder predefined portion of reverse osmosis reject effluent as feed to first Biomethanation and Anaerobic Digestion Module.

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The present disclosure relates to a single pot process for preparation of a N,N-di substituted carboxamide compounds of formula (I), said process comprising: reacting a carboxylic acid with a di-substituted carbamoyl chloride in presence of an organic tertiary base to obtain the N,N-di substituted carboxamide compounds of formula (I). The process of the present disclosure involves a simple step, and it is energy and time saving process for preparation of N, N-di substituted carboxamides.

A stationary concrete mixing drum - SCMD transit mixer for production & transportation of the concrete is provided. The mixer has a stationary concrete mixing drum with a top open (3) and two different sets of spirals mounted on a single shaft. The larger diameter spirals are called the discharging spirals & the smaller diameter spirals are called the mixing spirals. The shaft is driven by a heavy duty planetary reduction gearbox. Further, the gearbox is driven by a mechanical drive powered by a dedicated slave engine. The shaft is provided with a unidirectional rotation. However, a bidirectional movement of the concrete is achieved by means of the spirals. Thus mixing and discharging through a controlled gate is accomplished. The mixer is provided with a set of electronic load cells (4) to actually weigh all the ingredients. The mixer is typically mounted on a normal commercial truck. The mixer is alternatively operated by a truck PTO. The mixer can be alternatively mounted on a trolley/ trailer or towed by a tractor. The cost can be reduced by 50-55%.

The present invention relates to a bacterial strain useful for reducing the total dissolved solids (TDS) levels from industrial waste water. The microbe which is invented in the process is having the immense capacity to reduce TDS from 1100 to 500 in just 30 min and upto 50 in 24 hrs after application of microbe to waste water. Microbe which has been generated is named Triton which is a greek word and is synonym for Sea God. Industrial waste waters contain hazardous compounds which are treatment, and is very cost effective, with negligible waste water as a byproduct without harming the environment. This technology can be used to treat the industrial waste water and make it fit for reuse so that the available water is used again without disturbing the ground water table. Now a day' s water pollution is the biggest problem that is faced by the entire globe. So this is a step towards the problem to clean the water without using harmful chemicals,

The present invention relates to a novel in-situ process for preparing 1-(6- methylpyridin-3-yl)-2-[(4-(methylsulphonyl)phenyl]ethanone of the formula (I), which eliminates the isolation of ketosulfide stage and avoids use of methanesulfonic acid and alkali metal tungstate for the oxidation of ketosulfide to ketosulfone. This present invention also provides different novel crystalline forms of ketosulfone.