The device for controlled application of cold, which is in the form of a cannula, for locally controlled application of cold in the anorectal tract, comprises a main component of frustoconical shape and a head in the form of a stub end, the main component and the head being connected by means of a transitional zone of concave shape that causes sphincter pressure to hold the invention in the ideal position. Within, the device may contain a substance that can be cooled - possibly, preferably, propylene glycol - and on its outside may be covered by a lubricating substance, preferably neutral vaseline. The device may have rounded edges and have been produced from plastic.

The present invention relates to the use of compounds derived from 1,2,3,5-tetrasubstituted pyroles in conjunction with pharmaceutically acceptable excipients in the production of a drug that can be used to treat inflammatory diseases involving processes of cellular apoptosis, preferably diseases arising through sepsis caused by Gram‑negative bacteria. Said diseases include acute sepsis‑induced pulmonary diseases, acute sepsis‑induced respiratory distress syndrome, endotoxic or endotoxemic shock, septic peritonitis or trauma. The invention also comprises the pharmaceutical composition for treating said diseases.

The invention relates to a portable electrical generator which includes a heating plate and a cooling means between which at least one thermoelectric plate is arranged, which collects the electric current generated between the heating plate and the cooling means when the plate is at a higher temperature than that of the cooling means, thus creating a potential difference.

Device for assisting handicapped people in accessing swimming pools or surfaces at a different level, comprising a frame that can be transported by means of wheels (7), which is provided with a system of immobilization that employs chocks (8) and a locking microswitch, which vertically supports a structure (5) to which is secured an electric motor that actuates a worm connected to the lower part of an arm (1) that can rock in the vertical direction by means of a shaft, the upper part of which has an articulated assembly (2) coupled thereto which causes a chair connected to said assembly to undergo a rotary movement in the vertical direction. The chair has a sprocket that interacts with a component that is also toothed, in order to adjust the boarding position. The invention proposes a stand-alone, electric item of assistance equipment that is easy for the actual user to move and to handle.

The invention relates to a device for female sexual stimulation which includes a hollow phallus-shaped body housing a plurality of vibrating motors on the inside thereof, intended for stimulating the erogenous zones of a vagina.

The present invention relates to a device that is capable of determining the individual amounts of two gases that are being simultaneously adsorbed in a porous solid, which is in contact with a mixture of both gases having predetermined pressure and composition.

The use of a pentacyclic triterpene in the production of a pharmaceutical or neutraceutical composition to prevent or to treat a myocardial inflammatory disease, preferably acute or subacute myocarditis, to prevent or to treat a disease involving the appearance of calcium‑salt deposits, and to prevent or to treat a disease involving fibrotic accumulation. Preferably, said pentacyclic triterpene is oleanolic acid. The invention further relates to a pharmaceutical or neutraceutical composition that comprises a triterpene in conjunction with at least one pharmaceutically acceptable adjuvant and/or vehicle or, when the composition is neutraceutical, a neutraceutically acceptable adjuvant and/or vehicle, for treating or preventing a myocardial inflammatory disease, preferably acute or subacute myocarditis, for preventing or treating a disease involving the appearance of calcium‑salt deposits, and for preventing or treating a disease involving fibrotic accumulation. Preferably, said pentacyclic triterpene is oleanolic acid.

The invention is designed especially to prevent the oxidation of wine in bottles where the bottle content has not been totally consumed, the main features of the cap of the invention focussing on the fact that said cap incorporates a housing for an oxygen‑absorbing product, preferably a filter impregnated with duly treated active charcoal, such that said filter‑like structure accelerates the process of absorption of oxygen and any volatile acids, thereby preventing oxidation of the wine and thereby maintaining the organoleptic properties of the wine constant over a long period of time.

The invention relates to systems comprising homogeneous nanoparticles having an average size of less than 1 micrometer and containing at least a sorbitan ester, a macrogol ester, a macrogol ether or a derivative of same and, optionally, at least one component derived from oxyethylene and/or at least one component having an electric charge (positive or negative). According to the invention, the components are incorporated in a single step consisting in mixing two solutions. The invention also relates to the use of said systems as medicines or medical devices, in tissue engineering or regenerative medicine, for cosmetic, hygienic or nutritional uses, and in surface coatings. The invention further relates to methods for preparing same.

The invention relates to a tube for storing unit doses of drugs which includes an elongate outer casing (10) having two open ends; an inner structure inside said casing (10), which includes two opposite symmetrical walls (12) connected at the ends thereof and ribbed on the inner surfaces thereof such as to enable the insertion and fastening of a blister pack containing a unit dose of a drug in channels opposite to said walls (12); and a pulling means for inserting and extracting the inner structure from the outer casing (10). The invention also relates to a device and a method for filling said tube with unit doses of drugs, and to a cabinet for dispensing unit doses of drugs from said storage tube.