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[Parsed Query:ID:"WO2012151537"
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, QUERY:ID:"WO2012151537" STEMMING:null OFFICES:
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PATENTSCOPE
⇧
1. (WO2012151537) FINITE FULLY ADDRESSABLE NUCLEIC ACID NANOSTRUCTURES AS NANOCARRIERS FOR DELIVERY OF PHARMACEUTICALS
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Pub. No.:
WO/
2012
/151537
International Application No.:
PCT
/
US2012
/
036617
Publication Date:
08.11.2012
International Filing Date:
04.05.2012
IPC:
C40B 30/04
(2006.01)
C
CHEMISTRY; METALLURGY
40
COMBINATORIAL TECHNOLOGY
B
COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES,
IN SILICO
LIBRARIES
30
Methods of screening libraries
04
by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
Applicants:
PARABON NANOLABS, INC.
[
US
/
US
]; 11260 Roger Bacon Drive Suite 406 Reston, VA 20190 (
US
)
(For All Designated States Except
US
)
.
DWYER, Chris
[
US
/
US
]; (
US
)
(For
US
Only)
.
ZHONG, Hong
[CN/
US
]; (
US
)
(For
US
Only)
.
NORTON, Michael
[
US
/
US
]; (
US
)
(For
US
Only)
.
ARMENTROUT, Steven
[
US
/
US
]; (
US
)
(For
US
Only)
Inventors:
DWYER, Chris
; (
US
).
ZHONG, Hong
; (
US
).
NORTON, Michael
; (
US
).
ARMENTROUT, Steven
; (
US
)
Agent:
LATIMER, Matthew, T.
; Latimer IP Law, LLC P.O. Box 711200 Herndon, VA 20171 (
US
)
Priority Data:
61/482,448
04.05.2011
US
Title
(EN)
FINITE FULLY ADDRESSABLE NUCLEIC ACID NANOSTRUCTURES AS NANOCARRIERS FOR DELIVERY OF PHARMACEUTICALS
(FR)
NANOSTRUCTURES D'ACIDES NUCLÉIQUES FINIES ENTIÈREMENT ADRESSABLES EN TANT QUE NANOVECTEURS POUR L'ADMINISTRATION DE PRODUITS PHARMACEUTIQUES
Abstract:
(EN)
The present invention provides nanostructures that are particularly well suited for delivery of bioactive agents to organs, tissues, and cells of interest
in vivo
, and for diagnostic purposes. In exemplary embodiments, the nanostructures are complexes of DNA strands having fully defined nucleotide sequences that hybridize to each other in such a way as to provide a pre-designed three dimensional structure with binding sites for targeting molecules and bioactive agents. The nanostructures are of a pre-designed finite length and have a pre-defined three dimensional structure.
(FR)
La présente invention concerne des nanostructures particulièrement appropriées pour l'administration d'agents bioactifs aux organes, aux tissus et aux cellules d'intérêt
in vivo
, et pour une utilisation à des fins de diagnostic. Dans des modes de réalisation cités à titre d'exemple, les nanostructures sont des complexes de brins d'ADN possédant des séquences nucléotidiques entièrement définies qui s'hybrident entre elles de manière à engendrer une structure tridimensionnelle préconçue avec des sites de liaison pour cibler des molécules et des agents bioactifs. Les nanostructures ont une longueur finie pré-conçue et une structure tri-dimensionnelle pré-définie.
Designated States:
AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language:
English (EN)
Filing Language:
English (EN)