GB2010051242 SPIROCYCLIC AMIDE DERIVATIVES

13. (WO2011012896) SPIROCYCLIC AMIDE DERIVATIVES

Latest bibliographic data on file with the International Bureau

Pub. No.:		WO/2011/012896		International Application No.:		PCT/GB2010/051242
Publication Date:		03.02.2011		International Filing Date:		29.07.2010

IPC:

C07D 498/10 (2006.01), A61K 31/5386 (2006.01), A61P 1/00 (2006.01), A61P 11/00 (2006.01), A61P 13/00 (2006.01), A61P 17/00 (2006.01), A61P 19/00 (2006.01), A61P 25/00 (2006.01), A61P 27/00 (2006.01), A61P 29/00 (2006.01), A61P 35/00 (2006.01), A61P 37/00 (2006.01), A61P 9/00 (2006.01), C07D 519/00 (2006.01)

Applicants:

ASTRAZENECA AB [SE/SE]; S-151 85 Södertälje (SE) (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
PULMAGEN THERAPEUTICS (SYNERGY) LIMITED [GB/GB]; The coach House Grenville Court, Britwell Road Burnham, Slough SL1 8DF (GB) (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
ALCARAZ, Lilian [FR/GB]; (GB) (For US Only).
BAILEY, Andrew [GB/GB]; (GB) (For US Only).
KINDON, Nicholas [GB/GB]; (GB) (For US Only)

Inventors:

ALCARAZ, Lilian; (GB).
BAILEY, Andrew; (GB).
KINDON, Nicholas; (GB)

Agent:

ASTRAZENECA INTELLECTUAL PROPERTY; AstraZeneca AB S-151 85 Södertälje (SE)

Priority Data:

0913342.2

31.07.2009

Title

(EN) SPIROCYCLIC AMIDE DERIVATIVES
(FR) COMPOSÉS - 801

Abstract:

(EN)Spirocyclic amide derivatives of formula (I) wherein ArCH₂CH₂NH- represents a β-adrenoceptor binding group, processes for their preparation, pharmaceutical compositions containing them, a process for preparing such pharmaceutical compositions, their use in therapy, and intermediates for use in their preparation.
(FR)La présente invention concerne des dérivés amide spirocycliques de formule (I) dans laquelle ArCH₂CH₂NH- représente un groupe de liaison β-adrénocepteur, des procédés pour leur préparation, des compositions pharmaceutiques les contenant. L'invention concerne également un procédé de préparation de telles compositions pharmaceutiques, leur utilisation en thérapie, et des intermédiaires à utiliser pendant leur préparation.

Designated States:

AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).

Publication Language:	English (EN)
Filing Language:	English (EN)