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1. (WO2008060574) THERAPEUTIC CONTACT LENSES WITH ANTI-FUNGAL DELIVERY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/060574    International Application No.:    PCT/US2007/023952
Publication Date: 22.05.2008 International Filing Date: 13.11.2007
IPC:
A61K 9/14 (2006.01)
Applicants: AUBURN UNIVERSITY [US/US]; Office Of Technology Transfer, 215 E. Thach Avenue, Auburn, AL 36830 (US) (For All Designated States Except US).
BYRNE, Mark, E. [US/US]; (US) (For US Only).
COLLINS, Allison [US/US]; (US) (For US Only).
VAUGHAN, Asa, D. [US/US]; (US) (For US Only).
VENKATESH, Siddarth [IN/US]; (US) (For US Only)
Inventors: BYRNE, Mark, E.; (US).
COLLINS, Allison; (US).
VAUGHAN, Asa, D.; (US).
VENKATESH, Siddarth; (US)
Agent: OWENS Jonathan, O.; HAVERSTOCK & OWENS LLP, 162 North Wolfe Road, Sunnyvale, CA 94086 (US)
Priority Data:
60/858,584 13.11.2006 US
11/346,770 03.02.2006 US (Priority Withdrawn 01.04.2008)
Title (EN) THERAPEUTIC CONTACT LENSES WITH ANTI-FUNGAL DELIVERY
(FR) LENTILLE CORNÉENNE THÉRAPEUTIQUE DÉLIVRANT UN ANTIFONGIQUE
Abstract: front page image
(EN)A drug delivery system is disclosed. The drug delivery system includes a recognitive polymeric hydrogel through which a drug is delivered by contacting biological tissue. The recognitive polymeric hydrogel is formed using a bio-template, which is a drug or is structurally similar to the drug, functionalized monomers, preferably having complexing sites, and cross-linking monomers, which are copolymerized using a suitable initiator. The complexing sites of the recognitive polymeric hydrogel that is formed preferably mimic receptor sites of a target biological tissue, biological recognition, or biological mechanism of action. A system in accordance with an embodiment of the invention is a contact lens for delivering a drug through contact with an eye. In a particular embodiment of the invention, the drug is an anti-microbial, such as an anti-fungal agent for treatment of large animals, such as horses.
(FR)L'invention porte sur un système de distribution de médicaments comprenant un hydrogel de polymère recognitif par l'intermédiaire d duquel le médicament est délivrée par contact avec un tissu biologique. Ledit hydrogel est formé en utilisant un modèle bio, constitué d'un médicament ou d'une structure semblable, des monomères fonctionnalisé présentant de préférence des sites de complexage et des monomères réticulants copolymérisés à l'aide d'un initiateur approprié. Les sites de complexage de hydrogel miment de préférence les sites récepteurs du tissu biologique cible, la reconnaissance biologique, ou un mécanisme biologique d'action. Un système lié à une exécution de l'invention est constitué d'une lentille cornéenne délivrant un médicament par contact avec l'oeil. Dans une exécution particulière le médicament) est un anti-microbien par exemple un agent antimycosique de traitement de gros animaux tels que des chevaux.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)