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1. (WO2006040579) BIOACTIVE POLYMERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/040579    International Application No.:    PCT/GB2005/003976
Publication Date: 20.04.2006 International Filing Date: 14.10.2005
IPC:
A61K 31/785 (2006.01), A61P 35/00 (2006.01)
Applicants: THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW [GB/GB]; Gilbert Scott Building, University Avenue, Glasgow, Lanarkshire G12 8QQ (GB) (For All Designated States Except US).
UNIVERSITY OF STRATHCLYDE [GB/GB]; McCance Building, 16 Richmond Street, Glasgow, Lanarkshire G1 1XG (GB) (For All Designated States Except US).
UCHEGBU, Ijeoma [GB/GB]; (GB) (For US Only).
SCHÄTZLEIN, Andreas, G. [DE/GB]; (GB) (For US Only).
DUFÈS, Christine [FR/GB]; (GB) (For US Only)
Inventors: UCHEGBU, Ijeoma; (GB).
SCHÄTZLEIN, Andreas, G.; (GB).
DUFÈS, Christine; (GB)
Agent: KIDDLE, Simon; Mewburn Ellis LLP, York House, 23 Kingsway, London, Greater London WC2B 6HP (GB)
Priority Data:
0422877.1 14.10.2004 GB
Title (EN) BIOACTIVE POLYMERS
(FR) POLYMERES BIOACTIFS
Abstract: front page image
(EN)Various polymers, including cationic polyamine polymers and dendrimeric polymers, are shown to possess anti-proliferative activity, and may therefore be useful for treatment of disorders characterised by undesirable cellular proliferation such as neoplasms and tumours, inflammatory disorders (including autoimmune disorders), psoriasis and atherosclerosis. The polymers may be used alone as active agents, or as delivery vehicles for other therapeutic agents, such as drug molecules or nucleic acids for gene therapy. In such cases, the polymers' own intrinsic anti-tumour activity may complement the activity of the agent to be delivered.
(FR)Différents polymères, y compris des polymères de polyamine cationiques et des polymères dendrimériques possédant une activité anti-proliférative et se prêtant, en conséquence, au traitement de troubles caractérisés par une prolifération cellulaire indésirable, comme par exemple les tumeurs, les troubles inflammatoires, (y compris les troubles auto-immuns), le psoriasis et l'athérosclérose. Les polymères peuvent être utilisés seuls comme agents actifs, ou comme véhicules de support pour d'autres agents thérapeutiques, notamment des molécules de médicaments ou des acides nucléiques en vue de la thérapie génique. Dans de tels cas, l'activité antitumorale intrinsèque des polymères est susceptible de complémenter l'activité de l'agent à administrer.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)